摘要
目的探讨对子宫肌瘤患者采用开腹与腹腔镜下子宫肌瘤剔除术治疗对患者卵巢功能以及血清性激素水平的影响。方法选择医院2020年1—12月收治的子宫肌瘤患者80例,以随机数表法分组,对照组(n=40)予开腹子宫肌瘤剔除术治疗,观察组(n=40)予腹腔镜下子宫肌瘤剔除术治疗,比较两组手术相关指标(手术时间、术中出血量、排气时间、下床时间、住院时间),检测患者术前术后黄体生成素(LH)、促卵泡激素(FSH)水平评估患者卵巢功能,并检查术前术后血清孕酮(P)、雌二醇(E2)水平评估患者性激素水平。结果观察组手术时间为(58.63±18.20)min,较对照组长;观察组出血量为(58.35±12.27)mL、排气时间为(13.25±3.15)h、下床时间为(1.29±0.65)d、住院时间为(3.26±1.14)d,均优于对照组,差异有统计学意义(t=3.709、12.167、15.718、4.079、9.221,P<0.05)。术后观察组LH、FSH水平分别为(18.96±2.25)、(20.84±2.04)mIU/mL,均较对照组(21.40±2.36)、(22.69±1.97)mIU/mL更低,差异有统计学意义(t=4.733、4.126,P<0.05)。术后观察组P、E2水平分别为(10.72±2.90)μg/L、(139.65±17.11)pmol/L,均较对照组(15.46±2.82)μg/L、(195.81±18.63)pmol/L更低,差异有统计学意义(t=7.411、14.042,P<0.05)。结论对子宫肌瘤患者采用腹腔镜下剔除手术治疗较开腹手术对患者的损伤小,有利于患者康复,且可减少对卵巢功能的影响,能够改善血清性激素水平,值得推广。
Objective To investigate the effect of open and laparoscopic myomectomy on ovarian function and serum sex hormone levels in patients with uterine fibroids.Methods 80 patients with uterine fibroids were selected and treated in the hospital from January to December 2020.Grouped by random number table method,the control group(n=40)was treated with open myomectomy,and the observation group(n=40)was treated with laparoscopic myomectomy.The operation-related indicators(operation time,intraoperative blood loss,exhaust time,getting out of bed,hospitalization time)were compared between the two groups.The levels of luteinizing hormone(LH)and follicle-stimulating hormone(FSH)were detected before and after surgery to evaluate the ovarian function of patients.And check the serum progesterone(P)and estradiol(E2)levels before and after surgery to evaluate the sex hormone levels in patients.Results The operation time of the observation group was(58.63±18.20)min,which was longer than that of the control group;the bleeding volume of the observation group was(58.35±12.27)mL,the exhaust time was(13.25±3.15)h,the time to get out of bed was(1.29±0.65)d,and the hospitalization time was(3.26±1.14)d,which were all better than those of the control group,the difference was statistically significant(t=3.709,12.167,15.718,4.079,9.221,P<0.05).The levels of LH and FSH in the observation group after operation were(18.96±2.25)mIU/mL and(20.84±2.04)mIU/mL,respectively,both were lower than the control group(21.40±2.36)mIU/mL and(22.69±1.97)mIU/mL,the difference was statistically significant(t=4.733,4.126,P<0.05).The levels of P and E2 in the observation group were (10.72±2.90) μg/L and (139.65±17.11) pmol/L, respectively, which were higher than those in the control group (15.46±2.82) μg/L and (195.81±18.63) pmol/L, the difference was statistically significant (t=7.411, 14.042,P<0.05). Conclusion Laparoscopic excision surgery for uterine fibroids has less damage to patients than laparotomy, which is beneficial to patients' recovery. And can reduce the impact on ovarian function, can improve serum sex hormone levels, worthy of promotion.
作者
蒋淑丽
Jiang Shuli(Department of Gynecology,Pingyi County Traditional Chinese Medicine Hospital,Pingyi,Shandong Province,273300 China)
出处
《系统医学》
2022年第7期170-173,共4页
Systems Medicine
关键词
子宫肌瘤
开腹手术
腹腔镜
卵巢功能
性激素
术后康复
Uterine fibroids
Laparotomy
Laparoscopy
Ovarian function
Sex hormones
Postoperative rehabilitation
