摘要
目的探讨补脾益肾法在糖尿病牙周炎患者中的应用效果。方法选取2019年12月至2020年10月广州市番禺区市桥医院收治的66例糖尿病牙周炎患者作为研究对象,采用随机数字表法分为对照组(33例)和治疗组(33例),对照组采用常规西药治疗,治疗组在西药基础上联合补脾益肾中药进行治疗,比较两组患者治疗前后中医证候积分、血糖水平、牙周指标和不良反应的差异。结果治疗前,两组患者中医证候积分比较,差异无统计学意义(P>0.05);治疗后,治疗组中医证候积分水平低于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者空腹血糖和餐后2 h血糖水平比较,差异无统计学意义(P>0.05);治疗后,治疗组空腹血糖和餐后2 h血糖水平均低于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者牙周探测深度(PPD)、附着丧失(AL)、菌斑指数(PLI)和龈沟出血指数(SBI)水平比较,差异无统计学意义(P>0.05);治疗后,治疗组PPD、AL、PLI和SBI水平均低于对照组,差异有统计学意义(P<0.05)。两组患者不良反应总发生率比较,差异无统计学意义(P>0.05)。结论对糖尿病牙周炎患者采用补脾益肾法治疗可以有效改善患者临床症状,在稳定患者血糖水平的基础上不增加不良反应的发生,临床治疗效果显著。
Objective To explore the effect of the method of invigorating the spleen and kidney in the treatment of diabetic periodontitis patients.Methods A total of 66 patients with diabetic periodontitis admitted to Panyu County Shiqiao Hospital,Guangzhou City from December 2019 to October 2020 were selected as the research objects,and they were divided into control group(33 cases)and treatment group(33 cases)according to random number table method.The control group was treated with conventional western medicine,and the treatment group was treated with traditional Chinese medicine for invigorating the spleen and kidney on the basis of western medicine.The differences in traditional Chinese medicine syndrome scores,blood sugar levels,periodontal indicators and adverse reactions were compared between the two groups before and after treatment.Results Before treatment,the difference in traditional Chinese medicine syndrome scores between the two groups was not statistically significant(P>0.05).After treatment,the traditional Chinese medicine syndrome scores of the treatment group were lower than those of the control group,and the differences were statistically significant(P<0.05).Before treatment,there were no significant differences between the two groups of fasting blood glucose and the 2 hours postprandial blood glucose levels(P>0.05).After treatment,the fasting blood glucose and 2 hours postprandial blood glucose levels of the treatment group were lower than those of the control group,and the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in the levels of probing pocket depth(PPD),attachment loss(AL),plaque index(PLI)and sulcular bleeding index(SBI)between the two groups(P>0.05).After treatment,the levels of PPD,AL,PLI and SBI in the treatment group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Treatment of patients with diabetic periodontitis by invigorating the spleen and kidney can effectively improve the clinical symptoms of the patients,no increase in the occurrence of adverse reactions on the basis of stabilizing the blood sugar level of the patients,and the clinical treatment effect is significant.
作者
刘嘉尹
陈春凤
徐琳
LIU Jiayin;CHEN Chunfeng;XU Lin(Department of Stomatology,Panyu County Shiqiao Hospital,Guangdong Province,Guangzhou511400,China)
出处
《中国当代医药》
CAS
2022年第3期103-106,共4页
China Modern Medicine
基金
广东省广州市番禺区科技计划项目(2020-Z04-031)。
关键词
糖尿病
牙周炎
六味地黄丸
补中益气丸
不良反应
Diabetes mellitus
Periodontitis
Liuwei Dihuang Pills
Buzhong Yiqi Pills
Adverse drug reactions
