摘要
厌恶是人和动物最基本的情绪之一,起源于口腔对苦味(有毒)物质的排斥,常伴有恶心呕吐和远离诱发刺激的强烈愿望,具有回避潜在疾病威胁的功能。大量动物和人类研究表明,催产素、孕激素和雌激素不同程度地影响核心厌恶刺激的感知、核心厌恶情绪的产生与表达、条件性厌恶习得和厌恶表情识别。三种激素主要通过作用于五羟色胺、γ-氨基丁酸、乙酰胆碱和谷氨酸等神经递质受体,调节杏仁核、脑岛、前扣带回、壳核、梨状皮层、额中回等脑区活动,影响厌恶加工。未来研究应当在准确测量激素水平和控制实验任务难度的基础上,探究各激素对不同感觉通道厌恶加工的影响,及其性别的调节作用;同时结合脑成像技术和动物行为学,明确各激素影响厌恶加工的神经内分泌机制。
Disgust is an important basic emotion for human beings and animals, and it derives from distasteful oral responses to bitter(toxic) tastants, often accompanied with nausea and vomiting and a strong desire to stay away from the induced stimulus, and it has the function of avoiding potential disease threats. A large number of studies have shown that oxytocin, progesterone, and estrogens can affect perception,generation and expression of core disgust, as well as learning conditioned disgust and recognizing facial expression in varying degrees. These three hormones mainly affect the processing of disgust by modulating neurotransmitter receptors including serotonin, γ-aminobutyric acid, acetylcholine, and glutamic acid receptors, and thus affecting the activities of amygdala, insula, anterior cingulate gyrus, putamen, piriform cortex, and middle frontal gyrus. Future studies should explore the effects of these hormones on disgust in different sensory channels and also consider their moderating roles in different genders by accurately measuring hormone levels and controlling the task difficulties. In addition, researchers can combine neuroimaging technologies with behavioral studies to clarify the neuroendocrine mechanism of these hormones affecting disgust processing.
作者
张霞
雷怡
王福顺
ZHANG Xia;LEI Yi;WANG Fushun(Institute of Brain and Psychological Sciences,Sichuan Normal University,Chengdu 610066,China)
出处
《心理科学进展》
CSSCI
CSCD
北大核心
2022年第1期85-97,共13页
Advances in Psychological Science
基金
教育部人文社科基金项目(19YJAZH083)。
关键词
厌恶
催产素
孕激素
雌激素
神经生理机制
disgust
oxytocin
progesterone
estrogen
neurophysiological mechanism
