摘要
目的对某院碳青霉烯类抗生素的应用现状进行调查与分析,探讨其用药合理性。方法本研究选取武汉科技大学附属天佑医院2018年1月至2019年12月485例应用碳青霉烯类抗生素的患者为研究对象,从使用科室分布情况、品种临床应用情况、用药合理性评价情况共三个方面进行统计与分析。结果使用科室分布情况以重症医学科、呼吸内科和中西医结合科为主;品种临床应用情况以美罗培南和亚胺培南西司他汀使用频次最高;用药合理性评价情况,不合理用药病例占比为23.92%,以用法用量及配伍和病原学及疗效评估不合理原因居前,分别达到9.28%和5.57%。结论某医院碳青霉烯类抗生素的临床应用应加强管理,以促进碳青霉烯类抗生素的规范使用。
Objective To investigate and analyze the current situation of carbapenem antibiotics in a hospital,and to explore its medication rationality.Methods A total of 485 cases using carbapenem antibiotics in Tianyou Hospital Affiliated to Wuhan University of Science and Technology from January 2018 to December 2019 were selected as the research objects,and the statistics and analysis were made from three aspects:the distribution of departments using carbapenem antibiotics,the clinical application of varieties and the evaluation of medication rationality.Results The distribution of departments used was mainly the department of intensive medicine,the department of respiratory medicine and the department of integrated traditional Chinese and western medicine.Meropenem and imipenem cilastatin were the most frequently used varieties in clinical application.According to the evaluation of medication rationality,the proportion of cases with irrational drug use was 23.92%,and the irrational reasons of usage and dosage and etiology were the top ones,reaching 9.28%and 5.57%,respectively.Conclusion The clinical application of carbapenem antibiotics in a hospital should be strengthened to promote the standardized use of carbapenem antibiotics.
作者
易蕾
崔颖
康焕珍
YI Lei;CUI Ying;KANG Huanzhen(Department of Pharmacy,Tianyou Hospital Affiliated to Wuhan University of Science and Technology,Hubei,Wuhan 430064,China;Department of Oncology,Tianyou Hospital Affiliated to Wuhan University of Science and Technology,Hubei,Wuhan 430064,China)
出处
《中国医药科学》
2021年第22期129-132,191,共5页
China Medicine And Pharmacy
