摘要
慢性胰腺炎是指由各种病因引起的胰腺组织和(或)功能发生不可逆性改变的一种慢性炎症性疾病,近年来其发病率和患病率均呈上升趋势,患者腹痛反复发作及营养物质吸收不良将严重影响其生长发育和智力发展。较成人而言,儿童慢性胰腺炎具有基因突变发生率高、疼痛评估难度大的特点,且儿童耐受性和自控力差。经内镜逆行胰胆管造影和介入性超声内镜等微创治疗较外科治疗具有创伤小、恢复快、可重复性强等优点,可明显缓解临床症状。本文旨在阐述近年来儿童慢性胰腺炎内镜微创治疗的研究进展。
Chronic Pancreatitis is a chronic inflammatory disease caused by a variety of reasons,with irreversible changes in pancreatic tissue and/or function.In recent years,the prevalence and morbidity of pediatric chronic pancreatitis is on the rise.Repeated abdominal pain and malabsorption can have severe influence on growth and intelligence development of children.Compared to adult patients,pediatric patients have some unique characteristics such as high incidence of gene mutation,difficulty of accurate pain evaluation,low endurance and poor self-control.Unlike surgery,endoscopic treatments such as Endoscopic retrograde cholangiopancreatography(ERCP)and Interventional Endoscopic Ultrasound(EUS)are minimally-invasive and repeatable,from which patients can get a good recovery more quickly,with clinical symptoms relieved significantly.This article is a review about the progression of minimally-invasive endoscopic treatments in pediatric chronic pancreatitis.
作者
吕彦玮
王丹
胡良皞
LüYanwei;Wang Dan;Hu Lianghao(Department of Gastroenterology,Changhai Hospital,Naval Medical University,Shanghai,200433,China)
出处
《临床小儿外科杂志》
CAS
CSCD
2021年第7期606-611,共6页
Journal of Clinical Pediatric Surgery
基金
国家自然科学基金(编号:82070664、81900590、81770635)
上海市科技创新行动计划技术标准项目(编号:19DZ 12201900)
上海市卫计委智慧医疗专项(编号:2018ZHYL0229)
上海市扬帆计划(编号:19YF1446800)
上海市曙光计划(编号:20 SG36)
上海市晨光计划(编号:20CG42)。
关键词
胰腺炎
慢性/诊断
胰腺炎
慢性/治疗
内窥镜逆行胰胆管造影术
介入性超声内镜
治疗结果
Pancreatitis,Chronic/DI
Pancreatitis,Chronic/TH
Endoscopic Retrograde Cholangiopancreatography
Interventional Endoscopic Ultrasound
Treatment Outcome
