摘要
报道了一种在铜片上采用原位生长法制备Cu_(2)O-Ag表面增强拉曼光谱(SERS)基底的方法。通过优化制备Cu_(2)O时退火的温度和时间,以及制备Cu_(2)O-Ag时AgNO_(3)的浓度和反应时间,制备了Cu_(2)O-Ag基底,具有良好的拉曼增强效果。基底表面形成的凹形空间和均匀密布的Ag纳米粒子提供了丰富的SERS“热点”,且该基底具有较好的疏水性、均匀性、稳定性和灵敏度,对探针分子罗丹明6G的检测限为0.78 nM。该基底对多种违禁药物都有很好的灵敏度,拉曼强度与药物浓度具有良好的定量关系,孔雀石绿、恩诺沙星和呋喃西林的检测限分别为4.9 nM、0.72μM和0.12μM。本文方法具有工艺简单、成本低、SERS活性高等优点,在环境监测领域具有较好的应用前景。
This paper reports a method of fabricating the Cu_(2)O-Ag SERS substrate by in-situ growth on a copper sheet.The as-fabricated substrate has considerable Raman enhancement after we optimized the annealing temperature and time for Cu_(2)O fabrication and the AgNO3 concentration and reaction time for Cu_(2)O-Ag fabrication.In addition,the concave spaces on the substrate surface and the uniformly distributed Ag NPs provided rich SERS“hot spots”.The substrate also has good hydrophobicity,homogeneity,stability,and sensitivity,and it can detect R6G with the limit of detection(LOD)of 0.78 nM.Furthermore,the substrate has great sensitivity towards several prohibited drugs,and the Raman intensity has an excellent quantitative relationship with drug concentration.To be specific,the LODs for malachite green,enrofloxacin,and nitrofurazone are 4.9 nM,0.72μM,and 0.12μM,respectively.In conclusion,the proposed method has a simple process,low costs,and high SERS activity,indicating bright application prospects for environmental monitoring.
作者
刘二伟
杨增玲
韩鲁佳
黄圆萍
廖科科
Liu Erwei;Yang Zengling;Han Lujia;Huang Yuanping;Liao Keke(College of Engineering China Agricultural University,Beijing 100083,China)
出处
《光学学报》
EI
CAS
CSCD
北大核心
2021年第7期136-143,共8页
Acta Optica Sinica
基金
国家级农业绿色发展先行区项目(1sfz20200115-3)
教育部创新团队发展计划项目(IRT-17R105)。
