摘要
目的探讨特利加压素治疗上消化道出血的临床效果与安全性。方法80例上消化道出血患者,随机分为试验组和对照组,各40例。对照组患者采用奥曲肽治疗,试验组患者采用特利加压素治疗。比较两组患者临床疗效及不良反发生情况。结果试验组患者治疗总有效率87.5%高于对照组的67.5%,差异有统计学意义(P<0.05)。试验组不良反应发生率22.5%低于对照组的45.0%,差异有统计学意义(P<0.05)。结论采取特利加压素治疗上消化道出血患者临床效果显著,且不良反应少,值得临床推广。
Objective To discuss the clinical effect and safety of terlipressin in the treatment of upper gastrointestinal hemorrhage.Methods A total of 80 patients with upper gastrointestinal hemorrhage were randomly divided into experimental group and control group,with 40 cases in each group.The control group was treated with octreotide,and the experimental group was treated with terlipressin.The clinical efficacy and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of treatment 87.5%of the experimental group was higher than 67.5%of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 22.5%of the experimental group was lower than 45.0%of the control group,and the difference was statistically significant(P<0.05).Conclusion Terlipressin has remarkable clinical effect in the treatment of patients with upper gastrointestinal hemorrhage with less adverse reactions,and it is worthy of clinical promotion.
作者
孙勇
SUN Yong(ICU,Dalian Sixth People’s Hospital,Dalian 116021,China)
出处
《中国现代药物应用》
2021年第1期97-99,共3页
Chinese Journal of Modern Drug Application
关键词
特利加压素
奥曲肽
上消化道出血
Terlipressin
Octreotide
Upper gastrointestinal hemorrhage
