摘要
目的探讨饮水控制联合消毒洗手顺序干预在小儿手足口病中的应用效果。方法选择2017年5月至2019年6月小儿手足口病患者86例,随机分为对照组(n=43例)和观察组(n=43例)。对照组采用常规方法治疗,观察组在对照组基础上联合饮水控制、幼儿消毒洗手顺序干预,干预后15 d比较2组症状消失时间、生化指标水平、T淋巴细胞水平及干预依从性。结果观察组饮水控制联合幼儿消毒洗手顺序干预后口腔溃疡消退、手足疱疹消失、体温恢复、白细胞恢复正常及住院时间均短于对照组(P<0.05);2组干预后15 d AST、CK-MB及hs-CRP水平低于干预前(P<0.05);观察组干预后15 d AST、CK-MB及hs-CRP水平低于对照组(P<0.05);2组干预后15 d CD+3、CD+4、CD+4/CD+8水平高于治疗前(P<0.05),CD+8低于治疗前(P<0.05);观察组干预后15 d CD+3、CD+4、CD+4/CD+8水平高于对照组(P<0.05),CD+8低于对照组(P<0.05);观察组干预后15 d饮食控制、饮食指导、药物治疗、康复锻炼及定期复查依从性均高于对照组(P<0.05)。结论饮水控制联合幼儿消毒洗手顺序干预用于小儿手足口病患者中能缩短症状消失时间,改善患儿生化指标水平,增强其T淋巴细胞水平,提高患儿治疗依从性,值得推广应用。
Objective To investigate the application effects of drinking water control combined with disinfection and hand washing sequence intervention in children with hand-foot-mouth disease.Methods A total of children patients with hand-foot-mouth disease who were treated in our hospital were enrolled in the study,who were randomly divided into control group(n=43)and observation group(n=43).The patients in control group were treated by conventional methods,however,the patients in observation group,on the basis of control group,were treated by drinking water control combined with disinfection and hand washing sequence intervention,with an intervention course of 15 days for both groups.The intervention effects,and the,symptom disappearance time biochemical index level and intervention compliance were observed and compared between the two groups.Results After the intervention,the symptom disappearance time and the length of staying in hospital in observation group were significantly shorter than those in control group(P<0.05).The levels of AST,CK-MB and hs-CRP in both groups were significantly lower than those before intervention(P<0.05).The levels of AST,CK-MB and hs-CRP in observation group were significantly lower than those in control group(P<0.05).The levels of CD+3,CD+4,CD+4/CD+8 after intervention in both groups were significantly higher than those before intervention(P<0.05),moreover,which in observation group were significantly higher than those in control group(P<0.05).In addition the compliance with diet control,diet guidance,drug treatment,rehabilitation exercise and regular rechecking in observation group was significantly higher than that in control group(P<0.05).Conclusion The application of drinking water control combined with disinfection and hand washing sequence intervention in children with hand-foot-mouth disease can shorten the symptom disappearance time,improve the levels of biochemical indexes,and improve the treatment compliance of children with hand-foot-mouth disease.
作者
管剑峰
华琰
马静
姚娜
GUAN Jianfeng;HUA Yan;MA Jing(Department of Pediatrics,Affiliated Hospital of Soochow University Jiangsu,Wuxi 214000,China)
出处
《河北医药》
CAS
2020年第23期3573-3576,共4页
Hebei Medical Journal
关键词
饮水控制
幼儿消毒洗手顺序
小儿手足口病
生化指标
依从性
drinking water control
infant disinfection and hand washing sequence
pediatric hand-foot-mouth disease
biochemical indexes
compliance