摘要
目的为了解云南省昭通市手足口病不同病毒型的流行特征,为手足口病的防控提供指导建议,特对昭通市手足口病不同病毒型的流行特征进行季节性特征分析。方法应用集中度和圆形分布法分析昭通市2014—2017年手足口病不同病毒型别的流行特征。结果检测到的病原体主要为EV71、Cox A16以及其他肠道病毒,分别为216份,182份,294份,分别占57.45%,73.44%,67.11%。M为0.86,说明EV71型手足口病有很强的季节性。经Rayleigh检验,差异有统计学意义(Z=99.53,P<0.001)。ā=157°,发病高峰日为5月10日,与未分型类似(5月16日),高峰期为4月21日至6月1日,流行期为4月1日至6月21日。结论根据手足口病的潜伏期和疫苗产生保护作用的时间段,在高峰期进行手足口病疫苗的接种,对疫苗接种的时效性和针对性有很好的指导意义。
Objective To understand the epidemic characteristics of different virus types of hand,foot and mouth disease(HFMD)in Zhaotong City,and provide guidance and recommendations for the prevention and control of HFMD,and to analyze seasonal characteristics of different virus types of HFMD in Zhaotong City.Methods The epidemiological characteristics of different virus types of HFMD in Zhaotong City from 2014 to 2017 were analyzed using the concentration and circular distribution methods.Results The main pathogens detected were EV71,Cox A16 and other enteroviruses,which were 216,182,and 294,respectively,accounting for 57.45%,73.44%,and 67.11%.M was 0.86,indicating that EV71 had strong seasonality.The Rayleigh test showed statistically significant differences(Z=99.53,P<0.001).ā=157°,the peak day of onset was May 10,similar to untyped(May 16),the peak period was April 21-June 1,and the epidemic period was April 1-June 21.Conclusion According to the incubation period of hand-foot-mouth disease and the period of time during which the vaccine develops protective effects,vaccination of hand-foot-mouth disease vaccine at the peak period has a good guiding significance for the timeliness and pertinence of vaccination.
作者
陈莉华
彭霞
郑尔达
黄甜
贾毅晨
郝林会
沈秀莲
何继波
CHEN Lihua;PENG Xia;ZHENG Erda;HUANG Tian;JIA Yichen;HAO Linhui;SHEN Xiulian;HE Jibo(Epidemic surveillance,Public Health Emergency Treatment Center,Yunnan Provincial Center for Disease Control and Prevention,Kunming 650022,China)
出处
《公共卫生与预防医学》
2020年第3期64-67,共4页
Journal of Public Health and Preventive Medicine
基金
云南省应用基础研究计划青年项目(2018FD107)。
关键词
圆形分布
手足口病
病毒分型
Circular distribution method
Hand-foot-mouth disease
Virus typing
