摘要
目的探讨全凭静脉和静吸复合全身麻醉对老年肿瘤患者术后认知功能的影响。方法280例老年肿瘤患者按麻醉方式不同分为观察组和对照组,各140例。观察组行全凭静脉麻醉,对照组行静吸复合麻醉,对2组患者的手术指标和术后认知功能进行统计分析,采用MMSE量表对2组患者术前术后认知功能进行评价分析,统计2组患者术后认知功能障碍发生率,对比2种麻醉方式对患者术后认知功能的影响。结果2组手术时间、苏醒时间、拔管时间和应答时间等指标比较差异无统计学意义(P>0.05)。2组患者术前MMSE评分比较差异无统计学意义(P>0.05),术后3 h及术后24 h MMSE评分比较无差异,术后6 h及术后12 h 2组MMSE评分比较差异有统计学意义(P<0.05)。观察组患者术后1个月认知功能障碍发生率显著低于对照组,比较差异有统计学意义(P<0.05);术后3个月2组患者认知功能障碍发生率无统计学差异(P>0.05)。结论全凭静脉麻醉较静吸复合麻醉可加快恢复老年肿瘤患者术后认知功能,临床可推广。
Objective To discuss the effect of total intravenous and intravenous inhalation combined with general anesthesia on postoperative cognitive function in elderly patients with cancer after operation.Methods 80 cases of elderly tumor patients were divided into the observation group and the control group according to different anesthesia methods,140 cases in each group.Patients in the observation group were given total intravenous anesthesia and patients in the control group were given intravenous inhalation anesthesia.The operation indexes and postoperative cognitive function of the 2 groups were analyzed statistically,the preoperative and postoperative cognitive function of the 2 groups was evaluated and analyzed with MMSE scale,the incidence of postoperative cognitive impairment in the 2 groups was counted,and the effect of 2 anesthesia methods on postoperative cognitive function of patients was compared.Results There was no significant difference in operation time,recovery time,extubation time and response time between the 2 groups(P>0.05).There was no significant difference in MMSE score between the 2 groups before operation(P>0.05).There was no difference in MMSE score between the 2 groups at 3 hours and 24 hours after operation.There was significant difference in MMSE score between the 2 groups at 6 hours and 12 hours after operation(P<0.05).The incidence of cognitive impairment in one month was significantly lower than that in the control group(P<0.05).There was no significant difference in the incidence of cognitive impairment in 3 months after operation between the 2 groups(P>0.05).Conclusion Compare with intravenous inhalation anesthesia,total intravenous anesthesia can accelerate the recovery of cognitive function of elderly cancer patients after operation,and can be popularized in clinic.
作者
夏夏
叶刚
XIA Xia;YE Gang(The Central Hospital of Enshi Autonomous Prefecture,Enshi,445000)
出处
《实用癌症杂志》
2020年第5期856-859,共4页
The Practical Journal of Cancer
基金
湖北省卫生计生指导性项目(编号:WJ2015Z102)。
关键词
全凭静脉
静吸复合全身麻醉
老年肿瘤
术后认知功能
Total intravenous
Intravenous Inhalation Combined with general anesthesia
Elderly tumors
Postoperative cognitive function
