摘要
目的研究肺炎支原体肺炎(MPP)婴幼儿继发血小板增多症的临床特征及意义。方法回顾性研究、分析本院于2016年1月-2018年12月期间收治的65例MPP婴幼儿继发血小板增多症患儿为观察组(血小板计数> 400×10^9/L),另选择同期收治的65例MPP血小板正常婴幼儿为对照组(血小板计数=100~400×10^9/L),均给予检测特异性肺支原体MP-IgM、胸部影像学检查,并对比分析两组患儿的临床特征、实验室检测结果、胸部影像检查情况以及与血小板计数的相关性。结果两组对比啰音时间、咳嗽时间及喘息发生率差异无统计学意义(P>0.05);观察组患儿的住院时间、发热时间与最高体温均高于对照组(P<0.05);观察组患儿的难治性MPP与肺外并发症均多于对照组(P<0.05);观察组患儿的WBC、CRP、PCT、ESR、大叶性或节段性及多重病原体感染率均高于对照组(P<0.05)。结论针对MPP婴幼儿继发血小板增多症其临床特征与肺外并发症表现更为严重,临床可依据具体表现为患儿制定安全有效的治疗方案。
Objective To study the clinical features and significance of thrombocytosis in infants with Mycoplasma pneumoniae pneumonia(MPP). Methods A retrospective study and analysis of 65 children with MPP infants with secondary thrombocytopenia admitted to our hospital from January 2016 to December 2018 were observed(platelet count >400×10^9/L). 65 infants with normal MPP platelets were treated as control group, platelet count=100(400×10^9/L). All patients were tested for specific M. pneumoniae MP-IgM and chest imaging. The clinical analysis of the two groups was performed. Characteristics, laboratory test results, chest imaging findings, and correlation with platelet counts. Results There was no significant difference in the time of vocalization, coughing time and wheezing between the two groups(P>0.05). The hospitalization time, fever time and highest body temperature of the observation group were significantly higher than the control group(P<0.05);The refractory MPP and extrapulmonary complications were significantly higher in the group than in the control group(P<0.05). WBC, CRP, PCT, ESR, lobary or segmental and multiple pathogen infection rates were observed in the observation group. Both were significantly higher than the control group(P<0.05). Conclusion The clinical features and extrapulmonary complications of MPP infants with secondary thrombocytosis are more serious. Clinically, a safe and effective treatment plan can be developed according to the specific performance.
作者
宗进进
ZONG Jinjin(Department of Pediatrics,Tongzhou District People's Hospital,Nantong Jiangsu 226300,China)
出处
《中国继续医学教育》
2020年第12期95-97,共3页
China Continuing Medical Education
关键词
肺炎支原体
婴幼儿
继发血小板增多症
临床特征
血小板计数
肺外并发症
mycoplasma pneumoniae
infants
secondary thrombocytopenia
clinical features
platelet count
extrapulmonary complications
