摘要
本文整理了近15年针灸治疗子宫内膜异位症(EMS)的临床和实验研究文献,归纳分析针灸治疗该病的机制研究进展。以"针灸""子宫内膜异位症"和"acupuncture therapy""endometriosis"等为检索词检索2003年1月至2018年10月中国期刊全文数据库、维普、万方、中国生物医学文献数据库、Pubmed、Embase中的相关文献。最终筛选出针灸治疗EMS的临床研究论文41篇,动物实验研究论文18篇,并对其中涉及到作用机制的20篇研究(包括18篇动物实验研究和2篇临床试验)加以总结,从针灸对各种生长因子、酶、酶抑制剂等的影响来探讨针灸治疗EMS疼痛、抑制异位组织血管生成和侵袭黏附、调节免疫功能及调节内分泌的机制,并提出目前研究中的不足及展望,以期为临床针灸治疗EMS提供证据。
The clinical and experimental researches of acupuncture and moxibustion on endometriosis during past 15 years were collected.The research progress underling the mechanism of acupuncture and moxibustion on endometriosis was summarized.By taken Chinese characters,i.e."acupuncture-moxibustion"and"endometriosis"as well as the English words,i.e."acupuncture therapy"and"endometriosis"as the searching words,the relevant articles were retrieved from Pubmed,Embase,Chinese China National Knowledge Infrastructure,Wanfang Database,Chongqing VIP and the China Biology Medicine Disc etc.The retrieval time was from January 2003 to October 2018.As a result,41 articles of clinical studies and 18 articles of animal experiments were screened.Of them,20 articles(including 18 articles of animal experiments and 2 articles of clinical trial)are related to the mechanism underling acupuncture and moxibustion on endometriosis.In term of the impacts on growth factors,enzymes and enzyme inhibitors,the mechanism of acupuncture and moxibustion was explored on the analgesia for endometriosis,the inhibition of ectopic tissue angiogenesis and invasive adhesion,as well as the regulation of immune function and endocrine.Moreover,the limitation and prospect on the current researches were proposed so as to provide the more reliable evidence for clinical treatment of endometriosis with acupuncture and moxibustion.
作者
席瑾
曹星星
高友玲
程洁
夏有兵
XI Jin;CAO Xing-xing;GAO You-ling;CHENG Jie;XIA You-bing(Nanjing University of Chinese Medicine,Nanjing 210023,China;Xuzhou Medical University,Xuzhou 221004,Jiangsu Province)
出处
《针刺研究》
CAS
CSCD
北大核心
2019年第10期772-776,共5页
Acupuncture Research
基金
国家自然科学基金面上项目(No.81473767)
关键词
针灸
子宫内膜异位症
机制研究
综述
Acupuncture and moxibustion
Endometriosis
Mechanism research
Review
