摘要
目的总结小儿川崎病的临床特征,探讨川崎病患儿并发冠状动脉病变(CAL)的危险因素。方法回顾性分析58例川崎病患儿的临床表现、实验室和心脏彩超结果等临床资料,分析川崎病患儿并发CAL的危险因素。结果58例患儿中,93.1%患儿年龄<5岁,男女比例为2.63∶1。发热(100.0%)、口唇潮红皲裂(87.9%)为最常见的临床表现;实验室检查以白细胞计数、血小板计数、C反应蛋白和血沉升高为主要表现。共18例(31.0%)出现CAL,年龄<3岁、治疗前发热时间≥14d是川崎病患儿并发CAL的危险因素(均P<0.05)。结论川崎病常见于5岁以内的男童,发热、唇红皲裂对早期诊断有一定的意义。<3岁、治疗前发热时间≥14d的川崎病患儿并发CAL的风险增高。
Objective To summarize the clinical features of pediatric Kawasaki disease,and to explore the risk factors for complication of coronary artery lesion(CAL)in pediatric Kawasaki disease.Methods The clinical data of 58 children with Kawasaki disease were retrospectively analyzed,including clinical manifestations,laboratory and echocardiography results,and the risk factors for complication of CAL were analyzed in children with Kawasaki disease.Results Among the 58 children,93.1%of the children were younger than 5 years,and the ratio of boys to girls was 2.63:1.Fever(100.0%)and cracked and erythematous lips(87.9%)were the most common clinical manifestations;the main manifestations of laboratory tests included elevated WBC count,PLT count,C-reactive protein and erythrocyte sedimentation rate.CAL was found in 18(31.0%)cases,age<3 years and duration of fever before treatment≥14 days were the risk factors for complication of CAL in children with Kawasaki disease(all P<0.05).Conclusion Kawasaki disease is common in boys younger than 5 years,fever and cracked and erythematous lips have a certain significance in the early diagnosis.The risk of complication of CAL increases in Kawasaki disease children aged<3 years and with a duration of fever before treatment≥14 days.
作者
何海玲
赖武超
温志红
梁珍花
HE Hai-ling;LAI Wu-chao;WEN Zhi-hong;LIANG Zhen-hua(Department of Pediatrics,the People′s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China)
出处
《广西医学》
CAS
2019年第12期1502-1504,共3页
Guangxi Medical Journal
关键词
川崎病
临床特征
冠状动脉病变
危险因素
并发症
小儿
Kawasaki disease
Clinical feature
Coronary artery lesion
Risk factor
Complication
Children
