摘要
目的比较连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾功能衰竭的效果。方法选择我院2016年12月至2017年11月收治的100例重症急性肾功能衰竭患者为研究对象,回顾性分析其临床资料,依据不同透析方案将其分为观察组(连续性肾脏替代治疗)与对照组(间歇性血液透析治疗),各50例。比较两组患者治疗前、后肾功能、预后相关指标及随访1年的死亡率。结果治疗后,两组患者的BUN及Scr水平均低于治疗前,且观察组低于对照组(P<0.05);治疗后,两组患者的APACHE-Ⅱ评分均降低,且观察组患者的APACHE-Ⅱ评分、心律失常发生次数及24h尿量≥600mL的天数均优于对照组(P<0.05);观察组患者的死亡率低于对照组(P<0.05)。结论连续性肾脏替代治疗重症急性肾功能衰竭的效果优于间歇性血液透析,可恢复患者的肾功能,改善预后,降低患者的死亡风险。
Objective To compare the effects of continuous renal replacement therapy and intermittent hemodialysis in the treatment of severe acute renal failure. Methods A total of 100 patients with severe acute renal failure admitted in our hospital from December 2016 to November 2017 were selected as the study objects, and the clinical data of patients were retrospectively analyzed. According to the different dialysis methods, the patients were divided into observation group (continuous renal replacement therapy) and control group (intermittent hemodialysis therapy), with 50 cases in each group. The renal function before and after treatment, prognostic indicators and mortality after 1 year of follow-up in the two groups were compared. Results After treatment, the levels of BUN and Scr in the two groups were lower than those before treatment, and those in the observation group were lower than the control group (P<0.05). After treatment, the APACHE-Ⅱscores of both groups decreased, and the APACHE-Ⅱ score, the number of arrhythmias and the days of 24 h urine volume≥600 mL in the observation group were better than those of the control group (P<0.05). The death rate in the observation group was lower than the control group (P<0.05). Conclusion Continuous renal replacement therapy is superior to intermittent hemodialysis in the treatment of severe acute renal failure, it can restore patients' renal function, improve prognosis and reduce the risk of death.
作者
张海涛
刘西纺
鲁伟
ZHANG Hai-tao;LIU Xi-fang;LU Wei(the Hospital of Jingyang County, Xianyang 713700;Honghui Hospital, Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710054, China)
出处
《临床医学研究与实践》
2019年第19期44-46,共3页
Clinical Research and Practice
