摘要
目的:探讨子宫螺旋动脉血流超声检测结合血清孕酮检测对先兆流产患者妊娠结局的预测作用。方法:回顾性分析2017年3月-2018年3月于本院行产前检查的孕5~8周孕妇检查资料300例,根据其临床诊断分为正常妊娠组(n=150)及先兆流产组(n=150),其中先兆流产组中又细分保胎成功组(n=98)和保胎失败组(n=52),所有孕妇同时抽取血清检测其孕酮值,并行子宫螺旋动脉血流超声检测其搏动指数(PI)、阻力指数(RI)及收缩末期峰值/舒张末期峰值(S/D)情况,并进行比较。观察随访6个月后的妊娠结局,分析上述检测方法对妊娠结局的预测情况。结果:三组血清孕酮值由高至低排列为正常妊娠组>保胎成功组>保胎失败组(P<0.01);三组PI及RI值由高到低排序均为保胎失败组>保胎成功组>正常妊娠组(P<0.05),正常妊娠组S/D值明显低于其他两组(P<0.05),而保胎成功组及保胎失败组S/D值比较,差异无统计学意义(P>0.05);联合检测灵敏度为85.58%,特异度为97.65%,准确率为95.8%。结论:通过子宫螺旋动脉血流超声检测结合血清孕酮检测对于先兆流产患者结局有较为准确的预测作用,能为先兆流产治疗方式的选择提供有效的数据支撑。
Objective:To investigate the predictive effect of uterine spiral arterial blood flow ultrasound combined with serum progesterone test on pregnancy outcome in patients with threatened abortion.Method:A retrospective analysis of 300 cases of pregnant women’s 5-8 weeks examination data from March 2017 to March2018 in our hospital.They were divided into normal pregnancy group(n=150)and threatened abortion group(n=150)according to their clinical diagnosis.The threatened abortion group divided into the prevent miscarriages success group(n=98)and the prevent miscarriages failure group(n=52).All patients were simultaneously serum-tested for progesterone value,pulsatile index(PI),resistance index(RI),and end-systolic peak/enddip peak(S/D)measuredby uterine spiral artery blood flow ultrasound were compared.The pregnancy outcome after 6 months of follow-up were observed,the prediction of pregnancy outcomes by the above test methods were analyzed.Result:The serum progesterone levels of the three groups were ranked from high to low as thenormal pregnancy group>the prevent miscarriages success group>the prevent miscarriages failure group(P<0.01).The PI and RI of the three groups were ranked from low to high as the prevent miscarriages failure group>the prevent miscarriages success group>the normal pregnancy group(P<0.05).The S/D of the normal pregnancy group was significantly lower than that of the other two groups(P<0.05),but there was no significant difference in the S/D between the prevent miscarriages success group and the prevent miscarriages failure group(P>0.05).The combined detection sensitivity was 85.58%,the specificity was 97.65%,and the accuracy was 95.8%.Conclusion:Ultrasound detection of uterine spiral artery blood flow combined with serum progesterone detection has a more accurate predictive effect on the outcome of patients with threatened abortion,and can provide effective data support for the choice of treatment methods for threatened abortion.
作者
何黎
史妙丽
HE Li;SHI Miaoli(Zhongshan Torch Development Zone Hospital,Zhongshan 528437,China)
出处
《中国医学创新》
CAS
2019年第16期112-115,共4页
Medical Innovation of China
基金
中山市医学科研项目(2018A020012)
关键词
子宫螺旋动脉血流
孕酮
先兆流产
妊娠结局
Uterine spiral arterial blood flow
Progesterone
Threatened abortion
Pregnancy outcome
