摘要
"药食同源"是中医药的重要内容,也是指导中药复方保健食品研制的基础。历代本草中的上品、补品、养生方与药膳等,是中药复方保健品的理论宝库。国家"健康中国2030"的实施,我国大健康产业面临巨大机遇。开发一批具有中医药特点的中药复方保健食品,符合国家及社会需求。国内对于中药保健食品研究多集中在功能成分提取、制剂成型工艺、质量标准、功效评价等,但在中药保健食品的中医药理论与功能关联特点、功效评价及安全性评价规范、新产品研发评价体系和研发平台方面存在不足。该文基于实验室前期大量研究,提出的性效关联观点,基于建立的中药功能-药理-临床应用数据库系统、中药配伍数据库系统、中药性味现代研究数据库系统等,及中医药动物模型评价平台,建立中药复方保健食品功效研究、安全性评价、新产品研发评价体系和研发平台,为开发及评价中药复方保健食品提供了基础,阐释中药复方保健食品核心功效的现代科学内涵,有助于促进中药复方保健品的研发,在大健康中发挥重要的作用。
Homology of medicine and food is an important content in Chinese medicine and also works as the basis for guiding the development of compound health food containing Chinese materia medica. The top products,supplements,health care prescriptions,and medicinal meals in traditional herbal texts are the theoretical treasures of Chinese medicine compound health foods. With the implementation of the National Healthy China 2030,China’s major health industry faces with tremendous opportunities. It is necessary to develop a batch of compound health food containing Chinese materia medica with Chinese medicine characteristics,in line with the needs of the country and society. Domestic research on compound health food containing Chinese materia medica mainly focuses on the extraction of functional components,preparation molding processes,quality standards,and efficacy evaluation. However,there are still some deficiencies in the related characteristics of traditional Chinese medicine(TCM) theory and function,evaluation criteria of efficacy and safety,new product R&D evaluation system and R&D platform. Based on a large number of previous studies by this laboratory,the views in nature,flavor and efficacy relationship were put forward in this paper. Based on the establishment of the Chinese medicine function-pharmacology-clinical application database system,the Chinese medicine compatibility database system,the Chinese medicine nature and flavor modern research database system,and the evaluation platform for animal models of Chinese medicine;the efficacy study,safety evaluation system,new product research and development evaluation system as well as research and development platform were established,providing a basis for the development and evaluation of compound health food containing Chinese materia medica. The modern scientific connotation of the core efficacy of compound health food containing Chinese materia medica was explained as well,helpful to promote the research and development of compound health food containing Chinese materia medica and play an important role in general health.
作者
田硕
许二平
孙蓉
王进博
苗明三
乔静怡
白明
李孟艳
武晏屹
TIAN Shuo;XU Er-ping;SUN Rong;WANG Jin-bo;MIAO Ming-san;QIAO Jing-yi;BAI Ming;LI Meng-yan;WU Yan-yi(Henan University of Chinese Medicine,Zhengzhou 450046,China;School of Advanced Medical Science,Shandong University,Jinan 250012,China;National Committee on the Assessment of the Protected Traditional Chinese Medicinal Products,Center for Food Evaluation,State Administration for Market Regulation,Beijing 100070,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2019年第5期870-874,共5页
China Journal of Chinese Materia Medica
基金
国家"重大新药创制"科技重大专项(2017ZX09301071)
中原学者项目(162101510003)
河南省科技攻关项目(162102310181
172102310042)
河南省产学研究项目(172107000012)
关键词
中药保健
数据挖掘
功效评价
Chinese medicine health care
data mining
efficacy evaluation
