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泌乳期母乳脂肪酸变化及其多不饱和脂肪酸影响因素 被引量:5

Changes of Fatty Acid Profile of Breast Milk during Different Lactation Periods and Factors Influencing Polyunsaturated Fatty Acid Content
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摘要 采用气相色谱-质谱联用技术测定不同泌乳期母乳中脂肪酸的动态变化,并分析乳母血型、生育年龄、孕周、孕前身体质量指数(body mass index,BMI)、分娩方式和婴儿性别、胎次对成熟母乳中与婴儿生长发育直接相关的重要多不饱和脂肪酸(polyunsaturated fatty acid,PUFA),亚油酸(linoleic acid,LA)、α-亚麻酸(α-linolenic acid,ALA)、花生四烯酸(arachidonic acid,AA),二十碳五烯酸(eicosapentaenoic acid,EPA)、二十二碳六烯酸(docosahexaenoic acid,DHA)相对含量的影响。结果显示,饱和脂肪酸(saturated fatty acid,SFA)含量在初乳和成熟乳间差异显著(P<0.05),单不饱和脂肪酸(monounsaturated fatty acid,MUFA)含量随着泌乳期的延长逐渐降低,但差异不显著(P>0.05),PUFA含量在各泌乳期无显著差异(P>0.05),AA、DHA含量随着泌乳期的延长逐渐降低,在初乳、过渡乳中含量差异均不显著(P>0.05),但均显著高于成熟乳中含量(P<0.05);母乳中LA含量与婴儿性别有关,ALA含量与乳母孕前BMI有关,母乳中AA、EPA含量与乳母血型有关,DHA含量与乳母孕前BMI、乳母血型有关,均具有统计学意义(P<0.05)。 Gas chromatography-mass spectrometry(GC-MS)was used to determine the dynamic changes of fatty acids in breast milk during different lactation periods.The effects of maternal blood type,childbearing age,pre-pregnancy body mass index(BMI),mode of delivery,gestational age,infant sex and parity on the contents of polyunsaturated fatty acids(PUFAs)directly related to infant growth and development such as linoleic acid(LA),α-linolenic acid(ALA),arachidonic acid(AA),eicosapentaenoic acid(EPA),docosahexaenoic acid(DHA)in mature milk were analyzed.The results showed that the contents of saturated fatty acids(SFAs)in colostrum and mature milk were significantly different(P<0.05).The content of monounsaturated fatty acid(MUFA)decreased gradually with the prolongation of lactation period,but the difference was not significant(P>0.05).There was no significant difference in the content of total PUFAs during different lactation stages(P>0.05).The contents of AA and DHA decreased gradually with the prolongation of lactation;they were not significantly different between colostrum and transitional milk(P>0.05),but were significantly higher than those in mature milk(P<0.05).LA content in breast milk was relate to infant sex,ALA content was related to pre-pregnancy BMI,the contents of AA and EPA were related to maternal blood type,the content of DHA was related to pre-pregnancy BMI and maternal blood type;all these correlations were statistically significant(P<0.05).
作者 仲玉备 陈历俊 赵军英 董学艳 李菊芳 刘斌 常兰兰 陈树兴 姜铁民 ZHONG Yubei;CHEN Lijun;ZHAO Junying;DONG Xueyan;LI Jufang;LIU Bin;CHANG Lanlan;CHEN Shuxing;JIANG Tiemin(College of Food and Bioengineering,Henan University of Science and Technology,Luoyang 471023,China;National Maternal and Infant Health Dairy Research Center,Beijing 100163,China;Beijing Dairy Engineering Technology Research Center,Beijing 100163,China)
出处 《食品科学》 EI CAS CSCD 北大核心 2019年第4期237-243,共7页 Food Science
基金 北京市科技计划项目(D141100004814002 Z171100004517013) 奶牛产业技术体系北京市创新团队项目
关键词 气相色谱-质谱 母乳 脂肪酸 多不饱和脂肪酸 影响因素 gas chromatography-mass spectrometry(GC-MS) breast milk fatty acid polyunsaturated fatty acid(PUFA) factors
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