摘要
目的探讨右美托咪定联合复方麝香注射液治疗冠状动脉搭桥术后谵妄的效果。方法选取冠脉搭桥术后谵妄患者56例,随机分为右美托咪定组与联合治疗组。比较2组谵妄维持时间及治疗前后S100β蛋白浓度。结果联合治疗组的谵妄维持时间、S100β蛋白浓度均显著优于对照组(P <0. 05)。结论右美托咪定联合复方麝香注射液可以显著缩短冠状动脉搭桥术后谵妄持续时间,改善神经功能。
Objective To explore the clinical efficacy of dexmedetomidine combined with Compound Musk Injection in the treating delirium after coronary arterial bypass grafting.Methods Fifty-six patients with delirium after coronary arterial bypass grafting were randomly divided into dexmedetomidine group and combined group.The duration of delirium maintenance and the concentration of S100βprotein before and after treatment were compared between the two groups.Results Delirium maintenance time and S100βprotein concentration in the combined group were significantly better than those in the control group(P<0.05).Conclusion Dexmedetomidine combined with Compound Musk Injection can significantly shorten the duration of delirium after coronary arterial bypass grafting and improve neurological function.
作者
于超
张新黎
伍育旗
秦兰洲
YU Chao;ZHANG Xinli;WU Yuqi;QIN Lanzhou(Department of Intensive Care Unit,Yichang First People's Hospital,Yichang,Hubei,443000;Changyang County Hospital of Traditional Chinese Medicine,Yichang,Hubei,443000)
出处
《实用临床医药杂志》
CAS
2019年第1期78-80,共3页
Journal of Clinical Medicine in Practice
基金
国家青年科学基金项目(81501045)
关键词
右美托咪定
复方麝香注射液
冠状动脉搭桥术
谵妄
dexmedetomidin
Compound Musk Injection
coronary arterial bypass grafting
delirium
