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重组人干扰素α-2b凝胶治疗慢性宫颈炎合并高危型HPV感染的临床效果 被引量:5

Clinical Effect of Recombinant Human Interferon-2b Gel in Treatment of Chronic Cervicitis Complicated with High-risk HPV Infection
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摘要 目的观察重组人干扰素α-2b凝胶治疗慢性宫颈炎合并高危型HPV感染的疗效。方法选取2016年9月至2017年12月本院慢性宫颈炎合并高危型HPV感染患者60例,随机分成对照组(30例)应用复方沙棘籽油栓治疗,观察组(30例)应用重组人干扰素α-2b凝胶治疗。对比两组治疗后的总有效率及HPV转阴率。结果观察组治疗总有效率和HPV转阴率均要高于对照组,差异有统计学意义(P <0.05)。结论重组人干扰素α-2b凝胶治疗慢性宫颈炎合并高危型HPV感染,治疗有效率及HPV转阴率均高于复方沙棘籽油栓。 Objective To observe the efficacy of recombinant human interferon α-2b gel in the treatment of chronic cervicitis with high-risk HPV infection. Methods From September 2016 to December 2017,60 patients with chronic cervicitis complicated with high-risk HPV infection were randomly divided into control group(30 cases)and treated with Compound Hippophae rhamnoides seed oil suppository. The observation group(30 cases)was treated with recombinant human interferon α-2b gel. The total effective rate and the negative rate of HPV were compared between the two groups. Results The total effective rate and HPV negative conversion rate in the observation group were higher than those in the control group,and the difference was statistically significant(P <0.05). Conclusion Recombinant human interferon α-2 b gel is superior to Compound Hippophae rhamnoides seed oil suppository in treating chronic cervicitis with high-risk HPV infection,effective rate and negative rate of HPV.
作者 杜林霖 DU Linlin(Cili County People's Hospital,Hunan Zhangjiajie 427200,China)
机构地区 慈利县人民医院
出处 《大医生》 2018年第11期121-122,共2页 Doctor
关键词 慢性宫颈炎 HPV感染 重组人干扰素Α-2B凝胶 宫颈糜烂 chronic cervicitis HPV infection recombinant human interferon alpha-2b gel cervical erosion
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