摘要
目的分析11 246例新生儿听力筛查结果及其听力损失高危因素和潜在因素。方法 11 246例新生儿出生后48～72 h采用TEOAE进行听力初筛,未通过者于出生后30～42 d采用TEOAE和AABR联合复筛;复筛仍未通过者,在3个月内进行听力诊断性检查。结果 (1)高龄产妇新生儿听力初筛、复筛的未通过率和听力损失患病率高于适龄产妇(P <0. 01)。早产、过期妊娠的新生儿听力初筛、复筛的未通过率和听力损失患病率高于正常胎龄新生儿(P <0. 01);(2)高危新生儿新生儿听力初筛、复筛的未通过率和听力损失患病率高于正常新生儿(P <0. 01);(3)新生儿听力损失高危因素检出率从高到低依次为听力障碍家族史,2种及以上高危因素,其母耳毒性药物史,高胆红素血症,颅面部畸形,宫内感染,重度窒息史,住院天数超过5 d,出生体重<1 500 g;(4)新生儿听力损失潜在因素有其母流产史,妊娠期上呼吸道感染史,其父吸烟史、饮酒习惯。结论提倡优生优育,加强孕期保健,定期进行孕期检查,以降低听力损伤对新生儿造成的不良影响。
Objective To analyze the results of 11 246 neonatal hearing screening and the risk and potential factors of hearing loss. Methods A total of 11 246 cases of 48 - 72 h newborn infants were enrolled for hearing screening test by transient evoked otoacoustic emission （TEOAE）. Those who did not pass the screening were re-screened by transient evoked otoacoustic emission （TEOAE） and the rapid brain stem evoked potential （AABR） after the birth of 30 42 d. The re-screening who still not passed, were performed diagnostic audiometry within 3 months. Results （1）The advanced maternal age in newborn hearing screening non-through rate and re-screening non-through rate and hearing impairment rate was higher than the maternal age （P 〈 0. 01 ）. The hearing screening non-through rate and re-screening non-through rate and hearing impairment rate in the premature and prolonged pregnant newborns were higher than that of newborns with normal gestational age （ P 〈 0.01 ）. （2） Hearing screening non- through rate and re-screening non-through rate and hearing impairment rate in the high-risk neonatal were higher than the normal newborn （ P 〈 0. 01 ）. （3）Detection rate of the newborn with risk factors for hearing loss, from high to low, were as follows： family history, 2 or more risk factors for hearing loss, his mother during pregnancy using ototoxic drugs, hyperbilirubinemia, craniofacial, deformities, intrauterine infection, severe asphyxia hospitalization in NICU more than 5 d, baby weight 〈 1 500 g. （4）The potential factors of newborn hearing impairment included ： history of maternal abortion, history of upper respiratory tract infection during pregnancy, his father used to drink and smoke. Conclusion Promoting eugenics and strengthening prenatal care and regular prenatal examination can reduce negative effects of hearing loss on neonates.
作者
郭琪
李红军
姜丽
胡琪
许士佳
李玉茹
GUO Qi;LI Hong-jun;JIANG Li;HU Qi;XU Shi-jia;LI Yu-ru(Department of Otolaryngology,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)
出处
《哈尔滨医科大学学报》
CAS
2018年第3期275-278,共4页
Journal of Harbin Medical University
基金
哈尔滨市科学技术局项目(2015RAXYJ043)
