摘要
目的:探讨分析登革热伴出疹和伴出血患者肝肾功能、凝血功能等实验室检验差异。方法:选取120例登革热伴出疹和120例登革热伴出血的急性期患者为研究对象,测定所有患者的谷丙转氨酶(ALT)、门冬氨酸转移酶(AST)、乳酸脱氢酶(LDH)、肌酐(Cr)、肌酸激酶(CK)等肝肾功能指标和血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶原活动度(PTA)等凝血功能指标情况,并比较登革热伴出疹组与登革热伴出血组患者上述各指标之间的差异。结果:登革热伴出血组患者的ALT、AST、LDH、CK等肝肾功能指标与PT、APTT、PTA等凝血功能指标检测结果皆明显高于登革热伴出疹组患者,差异有统计学意义(P<0.05)。结论:登革热伴出血患者中肝肾功能、凝血功能损害程度高于登革热伴出疹患者,在临床上应予重视,以降低重症登革热的发生风险。
Objective： To analyze the laboratory detection differences of the liver and renal functions and blood coagulation functions in dengue fever patients accompanied by rash and bleeding. Methods： 120 dengue fever patients accompanied by rash and another 120 acute dengue fever patients accompanied by bleeding were selceted as the subjects, whose liver and renal indexes such as ALT, AST, LDH, Cr, CK, and such coagulation indexes as PT, APTF, and PTA were all determined. And the indexes of both groups were compared. Results： Liver and renal function indexes of ALT, AST, LDH and CK, and blood coagulation indexes of PT, APPT, PTA of the dengue fever patients accompanied by bleeding were obviously higher than those of the dengue fever patients accompanied by rash group, which were of statistical differences （P〈0.05）. Conclusion： The damage degree of liver and renal functions, and the blood coagulation functions of dengue fever patients accompanied by bleeding is more serious than that of those accompanied by rash, importace should be attacthed to clinical treatment in order to reduce the risk of severe dengue fever.
作者
林伟琦
曾培灿
LIN Weiqi;ZENG Peican(Dept.of Clinical Laboratory;The 1^st Integrated Department of the People＇ s Hopital of Chaozhou,Chaozhou 521000,China)
出处
《华夏医学》
CAS
2018年第3期43-46,共4页
Acta Medicinae Sinica
关键词
登革热
出疹
出血
肝肾功能
凝血功能
dengue fever
rash
bleeding
liver and renal function
coagulation function
