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右美托咪定对腹腔镜胆囊切除术病患七氟烷麻醉复苏期躁动的影响 被引量:5

Effect of Dexmedetomidine on Agitation During Recovery of Sevoflurane Anesthesia in Patients Undergoing Laparoscopic Cholecystectomy
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摘要 目的研究分析在腹腔镜胆囊切除术病患的七氟烷麻醉复苏期中,右美托咪定的临床价值。方法从2015年6月-2017年6月于我院接受诊疗并行腹腔镜胆囊切除术的病患中选取90例作为此次研究对象,将其按照诊疗顺序的不同进行随机分组,分为观察组(45例)和参照组(45例)。两组病患均利用七氟烷实施麻醉,手术结束前10 min,参照组静脉注射舒芬太尼,观察组静脉注射右美托咪定,研究分析两组病患的临床效果。结果观察组的七氟烷保持用量明显低于参照组,平均拔管时间明显短于参照组,且P<0.05;观察组的舒张压、收缩压和心率在全身麻醉苏醒拔管前(T2)和拔管时(T3)无显著改变,而参照组的舒张压、收缩压和心率在全身麻醉苏醒拔管前和拔管时显著升高,且P<0.05;观察组病患的术后疼痛和躁动情况明显优于参照组,参照组的躁动发生率(22.23%)明显高于观察组(2.22%),且P<0.05,差异有统计学上的意义。结论在腹腔镜胆囊切除术病患的七氟烷麻醉复苏期中,右美托咪定可以有效控制患者心血管应激反应,减少七氟烷麻醉剂的保持用量,减轻患者术后疼痛感,大大降低了患者术后躁动的发生率。 Objective To study the clinical value of dexmedetomidine in sevoflurane anesthesia during laparoscopic cholecystectomy. Methods From June 2015 to June 2017,90 cases of patients undergoing laparoscopic cholecystectomy in our hospital were selected as the study subjects. Patients were randomly divided into observation group( 45 cases) and the reference group( 45 cases). Both groups were sevoflurane anesthesia,10 min before the end of surgery,the reference group sufentanil intravenously,the observation group intravenous dexmedetomidine study to analyze the clinical effect of the two groups of patients. Results The maintenance dose of sevoflurane in the observation group was significantly lower than that of the reference group,and the average time of extubation was significantly shorter than that of the reference group( P〈0. 05).Before diastole( T2),the diastolic blood pressure,And extubation( T3),while the diastolic blood pressure,systolic blood pressure and heart rate in the reference group before anesthesia awake extubation and extubation were significantly increased,and P〈0. 05; The observation group patients with postoperative pain and agitation was significantly better than the reference group. The incidence of agitation in the reference group( 22. 23 %) was significantly higher than the observation group( 2.22 %),and P〈0. 05. The difference was statistically significant. Conclusion Dexmedetomidine can effectively control the cardiovascular stress response during sevoflurane anesthesia recovery in patients undergoing laparoscopic cholecystectomy and reduce the maintenance dose of sevoflurane anesthesia and relieve postoperative pain and greatly reduce the postoperative pain and the incidence of postoperative agitation in patients.
作者 黄敏贞 罗青 方建勤 何海峰 HUANG Minzhen;LUO Qing;FANG Jianqin;HE Haifeng
出处 《现代医院》 2018年第4期599-601,共3页 Modern Hospitals
关键词 腹腔镜胆囊切除术 右美托咪定 七氟烷 复苏 躁动 麻醉 Laparoscopic Cholecystectomy Dexmecletomidine Sevoflurane Recovery Restlessness Anesthesia
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