摘要
目的探究控制糖尿病患者孕期体质量指数(BMI)对妊娠结局、先兆子痫发生率的影响,为改善妊娠期糖尿病妊娠结局提供理论依据。方法选取2014年6月-2016年6月在该院诊断与治疗的妊娠期糖尿病患者200例,所有患者孕前BMI均≥24 kg/m^2,采用病历资料回顾性分析的方式进行妊娠结局、先兆子痫发生率的探究。其中将采用常规饮食及运动干预的100例患者设为对照组(妊娠期BMI≥24 kg/m^2),常规干预配合胰岛素治疗的100例患者设为观察组(妊娠期BMI<24 kg/m^2),比较两组孕妇娩出新生儿体质量、身长等基本资料,并详细记录先兆子痫、巨大儿、早产、胎儿窘迫等发生情况。结果观察组新生儿出生身长为(50.40±2.40)cm,显著低于对照组的(51.10±2.50)cm,观察组新生儿出生体质量为(3.36±0.32)kg,显著低于对照组的(3.51±0.34)kg,两组孕妇娩出新生儿体质量、身长比较差异均有统计学意义(t=2.020,P=0.045;t=3.213,P=0.002)。观察组先兆子痫、巨大儿、早产、胎儿窘迫发生率均显著低于对照组(P<0.05)。结论控制妊娠期糖尿病患者孕期BMI能改善妊娠结局,显著降低先兆子痫、巨大儿、早产、胎儿窘迫等不良妊娠结局的发生率,新生儿体质量较孕期BMI≥24 kg/m^2者更轻。
Objective To explore the effect of controlling body mass index （BMI） during pregnancy on pregnancy outcomes and inci- dence rate of preeclampsia in patients with diabetes, and provide a theoretical basis for improving pregnancy outcomes of patients with gesta- tional diabetes mellitus （GDM） . Methods A total of 200 patients with GDM （BMI before pregnancy 〉124 kg/m2） diagnosed and treated in People＇s Hospital of Zhao County from June 2014 to June 2016 were selected. The pregnancy outcomes and incidence rate of preeclampsia were analyzed retrospectively. The patients were divided into control group （BMI during pregnancy ≥ 24 kg/m2, routine diet and exercise in- tervention） and observation group （BMI during pregnancy〈24 kg/m2, routine intervention combiend with insulin therapy） . The basic data of neonates born by the pregnant women in the two groups were compared, including neonatal weight and height. The prcvalence rates of prc- eclampsia, macrosomia, preterm birth, and fetal distress were recorded detailedly. Results Neonatal birth height in observation group was （50. 40±2. 40） cm, which was significantly lower than that in control group [ （51.10±2. 50） cm], neonatal birth weight in observation group was （3.36±0. 32） kg, which was signifieantly lower than that in control group [ （3.51±0. 34） kg] , there were statistically signifieant differences in neonatal birth height and weight between the two groups （ t = 2. 020, P = 0. 045 ; t = 3. 213, P = 0. 002） . The incidence rates of preeclampsia, macrosomia, preterm birth, and fetal distress in observation group were statistically significantly lower than those in control group （ P〈0. 05 ） . Conclusion Controlling BMI of GDM patients during pregnancy can improve pregnancy outcomes and significantly re- duce the incidence rates of preeclampsia, macrosomia, preterm birth, fetal distress, and other adverse pregnancy outcomes. Neonatal weight is lighter than that of those born by pregnant women with BMI≥24 kg/m2 during pregnancy.
出处
《中国妇幼保健》
CAS
2018年第5期988-990,共3页
Maternal and Child Health Care of China
基金
石家庄科技局课题(161462673)
关键词
妊娠期糖尿病
体质量指数
妊娠结局
先兆子痫
Gestational diabetes mellitus
Body mass index
Pregnancy outcome
Preeclampsia
