摘要
目的分析咸阳市HIV抗体不确定结果的特征、产生的原因和对艾滋病防控工作的影响。方法对2010-2016年咸阳市艾滋病确证实验室免疫印迹试验方法检测发现的112例HIV抗体不确定病例及随访的54例进行描述,并采用卡方检验对结果进行分析。结果 112例不确定病例中,无偿献血占59.82%(67/112)、医院病人占31.25%(35/112)、自愿咨询检测(VCT)人群占8.92%(10/112)。不同人群的不确定病例阳转率差异无统计学意义(χ~2=4.370,P>0.05)。不确定条带有7种带型,其中构成比排在前3位的分别是p24、gp160和gp160,p24占不确定样本总数的88.39%。54例完成随访检测,占48.21%(54/112)。其中35例转阴条带类型中以p24带型为主;12例转阳带型中Env类条带不确定的占84.21%(16/19)。结论加强不确定病例的随访,提高受检者HIV抗体诊断效率,做到尽早诊断、尽早治疗。
Objective To analyze the characteristics, causes and effects of the HIV antibody indeterminate results in Xianyang City. Methods 112 cases of HIV antibody uncertainty and 54 cases of follow - up were described by western blot test of HIV/ AIDS confirmatory laboratory in Xianyang City from 2010 to 2016, and the results were analyzed with chi - square test. Results Of the 1t2 cases, 59. 82% （67/112） were hospitalized, 31.25% （35/112） were hospitalized, and 8. 92% （10/112） were voluntary counseling and testing（ VCT）. There was no significant difference in the positive rate of uncertainty among different groups（x2 = 4. 370, P 〉 0. 05）. There are 7 bands of indeterminate bands, of which p24, gpl60 and gpl60, p24 constitute 88.39% of the total number of uncertain samples. 54 patients were followed up for 48.21% （54/112）. Among them, p24 ban- ding type was the main type in 35 cases of negative banding, Env class band uncertainty accounted for 84. 21% （16/19） among 12 seroconversion class trips. Conclusion To strengthen the follow - up of uncertain cases and improve the efficiency of HIV antibody diagnosis in the subjects, early diagnosis and treatment as soon as possible with patients.
出处
《医学动物防制》
2017年第11期1138-1141,共4页
Journal of Medical Pest Control
基金
陕西省2016年中央公共卫生艾滋病防治专项(陕财办社[2016]133号
咸财社保[2016]215号)
