摘要
目的:探讨雪峰虫草在补肾助阳及抗疲劳方面的作用。方法:通过建立雄性去势大鼠模型和氢化可的松致小鼠肾阳虚模型,观察雪峰虫草对去势大鼠的附性器官、性激素水平的影响及抗疲劳作用。结果:雪峰虫草小、中、高剂量组能显著缩短大鼠阴茎勃起时间,增加大鼠包皮腺指数、精囊腺+前列腺指数;能显著增加肾阳虚小鼠自主活动次数、负重游泳时间,并且雪峰虫草中、高剂量组能显著增加小鼠实验后体质量,与模型对照组比较,差异均有统计学意义(P<0.05或P<0.01)。结论:雪峰虫草具有较好的补肾助阳和抗疲劳作用。
Objective： To investigate the kidney-tonifying,yang-strengthening,and anti-fatigue effects of Ophiocordyceps xuefengensis. Methods： A model of male castrated rats and a mouse model of kidney-yang deficiency induced by hydrocortisone were established,and the effect of Ophiocordyceps xuefengensis on accessory sex organs and sex hormone levels and its anti-fatigue effect were observed. Results： Low-,middle-,significantly shortened the time to penile erection and increased preputial gland index and seminal vesicle ＋ prostate index in rats; meanwhile,it significantly increased the number of locomotor activities and duration of loaded swimming in mice with kidney-yang deficiency,and compared with the model control group,the middle-and high-dose Ophiocordyceps xuefengensis groups had a significant increase in body weight after experiment（ P〈0. 01 or P〈0. 05）. Conclusion： Ophiocordyceps xuefengensis has good kidney-tonifying,yang-strengthening,and anti-fatigue effects.
出处
《湖南中医杂志》
2017年第7期164-166,共3页
Hunan Journal of Traditional Chinese Medicine
基金
湖南省科学技术重大专项资助项目(编号:2014FJ1007)
湖南省中医药科研计划项目(编号:201267
201322)
关键词
雪峰虫草
补肾助阳
抗疲劳
实验研究
Ophiocordyceps xuefengensis
kidney-tonifying and yang-strengthening
anti-fatigue
experimental study
