摘要
脑白质疏松症是指脑室周围或皮质下区(半卵圆中心)弥漫性非特异性白质损害。脑白质疏松症可以增加脑卒中的风险,并与认知功能下降和运动障碍等密切相关。已有研究认为高血压病是脑白质疏松症最主要的危险因素。但随着对脑白质疏松症形成的病理生理机制研究的不断完善,学者们发现低血压及血压变异性也与脑白质疏松症相关。文中旨在对血压及其变异性与脑白质疏松症之间的联系研究进行综述。
Leukoaraiosis （LA） is a group of clinical syndrome used to describe diffuse white matter abnormalities on computer tomography or magnetic resonance imaging brain scans, which increases the risk of stroke, cognitive and mobility impairment. Hypertension tends to be the most important risk factor of LA. However, with the development of LA pathophysiological mechanism study, hypotension and blood pressure variability have been found to be related to LA. The relationships between LA and blood pressure and its variability were summarized.
出处
《中国临床神经科学》
2017年第2期241-244,F0003,共5页
Chinese Journal of Clinical Neurosciences
基金
国家自然科学基金面上项目(编号:81271303)
关键词
脑自质疏松症
血压
血压变异性
动态血压监测
leukoaraiosis
blood pressure
blood pressure variability
ambulatory blood pressure monitoring
