摘要
目的显微血管减压术(MVD)是治疗原发性三叉神经痛(TN)的有效方法,但MVD预后影响因素目前仍存在很多争议。本文通过5年时间的随访观察MVD的疗效,并运用统计学方法筛选出可能的预后影响因素。方法对2011年01月至2015年12月之间我院神经外科所收治的首次行显微血管减压术治疗的原发性TN患者每年至少随访一次,对所获取的数据通过Logistic回归分析筛选出可能的预后影响因素。结果在这些患者中,典型性三叉神经痛患者术后疼痛的立即完全缓解率为79.8%,随访两年以上的疼痛完全缓解率为88.0%;而非典型三叉神经痛患者术后疼痛的立即缓解率为71.8%,随访2年以上的疼痛完全缓解率只有45.0%。Logistic回归分析发现典型的TN症状、责任血管或者主要责任血管为动脉、术后疼痛立即缓解是预后的有利因素(均P<0.05)。结论MVD是治疗原发性TN的有效外科手术,典型的三叉神经痛症状、责任血管或者主要责任血管为动脉、术后疼痛立即缓解是预后的有利因素。
Objective The microvascular decompression （MVD） is an effective method for the treatment of primary trigeminal neuralgia （trigeminal Neuralgia, TN）, but much controversy over MVD prognostic factors stil exists. In this paper, the efficacy of MVD was observed within 5 years of follow-up, and the statistical methods were used to screen the possible prognostic factors. Methods The primary TN patients first treated by mierovascular decompression from December 2011 to January 2015 were followed up at least once a year and all the data were collected and analyzed by Logistic regression analysis to identify the possible prognostic factors. Results In patients, typical trigeminal neuralgia patients with post-operative pain immediate complete remission rate was 79. 8% and the pain complete remission rate was 88.0% during the foUow-up for more than two years ; and the atypical trigeminal neuralgia patients pain of immediate relief rate was 71.8% and pain complete remission rate was only 45.0% during the follow-up for more than 2 years. Logistic regression analysis found that the typical symptoms of TN, the responsibility of blood vessels or the main responsibility for the artery, post-operative pain relief was the favorable factors （P 〈 0. 05）. Conclusion MYD is an effective surgical procedure for the treatment of primary TN. The characteristic symptons of TN, the responsible vessels and immediate relief of pain after surgery are the favorable factors for the prognosis of the patients.
作者
王马军
赵明
杜国森
徐龙彪
潘柏林
韦超
王宁
郭宣明
吴天涯
WANG Majun ZHAO Ming DU Guosen XU Longbiao PAN Bolin WEI Chao WANG Ning GUO Xuanming WU Tianya(Department of Neurosurgery, Zhejiang Zhufi People＇s Hospital, Zhuji 311800, China)
出处
《中华神经外科疾病研究杂志》
CAS
2017年第2期142-145,共4页
Chinese Journal of Neurosurgical Disease Research
关键词
微血管减压术
三叉神经痛
随访
Microvascular decompression
Trigeminal neuralgia
Follow-up
