摘要
病害问题是阻碍水产养殖产业发展的瓶颈之一。抗生素等药物的大量使用,易造成致病菌抗药性,危害环境和食品安全。聚β-羟基丁酸酯(PHB)是短链脂肪酸β-羟基丁酸的聚合体,为热塑性聚酯,具有生物可降解性、生物相容性等特点。研究表明,在碳、氮营养失衡的情况下,细菌胞内可以积累PHB作为碳源和能量储备;此外,PHB能够抑制致病菌,且不产生抗药性。本文综述了PHB的结构特性、合成和检测方法,介绍了其在水产动物中的作用,并展望了PHB在水产动物肠道免疫中未来的研究趋势。
Bacterial diseases hamper the further development of aquaculture industry. The misuse of antibiotics may cause antibiotic resistance, impair the effectiveness of antibiotic treatment and is harmful for the environment. Poly-β hydroxybutyrate （PHB）, a novel disease control agent, is a synthetic thermoplastic polyester and a polymer of short chain fatty acids β-hydroxybutyric acid, with the characteristics of biodegradability and biocompatibility. PHB serves as an intracellular energy and carbon reserve of bacteria. This paper reviewed the structure characteristics, synthesis and testing methods of PHB, introduced the status of researches on the function of PHB in aquacultural animal health and disease control, and prospected the research and application trend of PHB in aquaculture industry.
作者
段亚飞
张月
张家松
董宏标
牛宇峰
李华
刘青松
DUAN Yafei ZHANG Yue ZHANG Jiasong DONG Hongbiao NIU Yufeng LI Hua LIU Qingsong(Key Laboratory of South China Sea Fishery Resources Exploitation ＆ Vtilization, Ministry of Agriculture, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China Lahoratory of Aquaculture, Ghent University, Gent 9000, Belgium)
出处
《海洋湖沼通报》
CSCD
北大核心
2017年第1期57-62,共6页
Transactions of Oceanology and Limnology
基金
国家科技支撑计划(2011BAD13B10)
中央级公益性科研院所基本科研业务费专项资金(中国水产科学研究院南海水产研究所)(2014TS15)
广东省海洋渔业科技推广专项(A201501B15,A201508B05)资助
