摘要
目的探讨血必净对感染性休克患者血乳酸(LA)、降钙素原(PCT)、C-反应蛋白(CRP)及血流动力学的影响,为感染性休克治疗提供参考。方法选取2014年1月-2015年8月于医院收治的感染性休克患者80例,随机分为观察组与对照组各40例,均给与规范化治疗,观察组患者同时给与血必净注射液静脉滴注,对比两组患者疗效,及其对血乳酸(LA)、降钙素原(PCT)、C-反应蛋白(CRP)及血流动力学的影响;数据采用SPSS 19.0软件进行统计分析。结果观察组与对照组治疗后与治疗前临床指标比较,均明显下降;观察组治疗总有效率为92.50%,高于对照组75.00%,差异均有统计学意义(P<0.05)。结论血必净用于感染性休克的治疗具有抑制机体炎症反应、改善血流动力学的效果,有助于提高治疗疗效。
OBJECTIVE To observe the Influence of Xuebijing injection on LA,PCT,CRP and hemodynamics in patients with septic shock,so as to provide a reference for treatment of septic shock.METHODS A total of 80 cases of patients with septic shock in our hospital from Jan.2014 to Aug.2014 were selected,and randomly divided into observation group and control group,with 40 cases in each group.The patients in the two groups were all given septic shock standardized treatment,and the patients in observation group at the same time were given the Xuebijing injection intravenous drip.The curative effects,the influence on LA,PCT,CRP and hemodynamics were compared.The data were analyzed by SPSS 19.0.RESULTS Compared with before treatment,the clinical indexes of observation group and control group were significantly decreased after treatment.The total effective rate of observation group was 92.50%,higher than 75.00% of control group（P〈0.05）.CONCLUSION Xuebijing injection for the treatment of septic shock can inhibit the body＇s inflammatory response,improve hemodynamic effect,and help to improve treatment efficacy.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3378-3380,共3页
Chinese Journal of Nosocomiology
基金
河南省科技厅基金资助项目(PL20120618)
关键词
血必净
感染性休克
乳酸
血流动力学
Xuebijing injection
Septic shock
Lactic acid
Hemodynamics
