摘要
目的探讨牙周基础治疗疗法对侵袭性牙周炎患者的疗效。方法选取2013年8月~2015年8月我院接收的侵袭性牙周炎68例患者,均给予牙周基础治疗,观察治疗前后牙周相关指标及牙齿松动情况、血清及龈沟液中肿瘤坏死因子-α（TNF-α）及白介素-4（IL-4）水平变化。结果治疗后1个月,患者探诊深度（PD）、出血指数（BI）、附着丧失（AL）均出现显著下降（P〈0.05）,至治疗后3个月,上述指标与治疗前比较差异均有统计学意义（P〈0.05）;治疗后3个月,患者牙齿无松动比例显著优于治疗前（P〈0.05）。血清中TNF-α、IL-4治疗后3个月与治疗前比较,差异无统计学意义（P〉0.05）;龈沟液中TNF-α、IL-4治疗后3个月与治疗前比较,差异有统计学意义（P〈0.05）。结论侵袭性牙周炎患者采取牙周基础治疗可显著改善牙周状况,改善牙松动状况,疗效显著。
Objective To study the clinical effect of periodental non-surgical treatment in patients with aggressive periodontitis.Methods 68 patients with aggressive periodontitis treated by periodetal non-suryery from August 2013 to August 2015 in our hospital were selected.The periodental index,gomphiasis as well as the level of TNF-α and IL-4 in serum and gingival crevicular fluid were observed.Results After treatment for 1 month,the level of probing depth（PD）,bleeding index（BI）,attachment loss（AL） was greatly reduced（P〈0.05）;After treatment for 3 months,the level of PD,BI,AL was significantly lower than before treatment（P〈0.05）;After treatment for 3 months,the rate of no gomphiasis was significantly better than before treatment（P〈0.05）.The level of serum tumor necrosis factor-α（TNF-α） and interleukin-4（IL-4） before treatment and after treatment for 3 months was not signifcant difference（P〉0.05）;The level of TNF-α and IL-4 of gingival crevicular fluid before treatment and after treatment for 3 months was signifcant difference（P〈0.05）.Conclusion The periodental non-surgical treatment has an obvious effect on patients with aggressive periodontitis,and can greatly improve the periodental condition and gomphiasis.
出处
《中国当代医药》
2016年第17期116-118,共3页
China Modern Medicine
关键词
侵袭性牙周炎
牙周基础治疗
疗效
Aggressive periodontitis
Periodental non-surgical treatment
Clinical effect
