摘要
目的观察耻骨上膀胱切开取石术、气压弹道碎石术联合前列腺电切术、钬激光碎石术联合前列腺电切术,同时联用药物治疗良性前列腺增生伴发膀胱结石患者的疗效。方法选取2010年1月至2015年1月经大连医科大学附属第一医院确诊的前列腺增生合并膀胱结石患者121例,随机分为开放手术组(n=45)、气压碎石组(n=39)和钬激光碎石结组(n=37)进行手术,术后应用坦索罗辛(0.2 mg/d)和(或)非那雄胺(5 mg/d)治疗。记录三组患者的术中情况及术后指标。结果开放手术组的取石时间、手术时间均较其余两组短(P<0.05);气压碎石组和钬激光碎石组的术中出血量、术后最大尿流率、住院时间、术后膀胱冲洗及导尿管滞留时间均优于开放手术组,差异有统计学意义(P<0.05);三组并发症的比较差异无统计学意义(P>0.05)。气压碎石组和钬激光碎石组相比,仅在取石时间上差异有统计学意义(P<0.05)。结论相较于开放手术,气压弹道碎石术和钬激光碎石术联合前列腺电切术具有操作简便、创伤小、术中出血少、风险较低等优点,具有很高的临床应用价值。
Objective To investigate the clinical efficacy of suprapubic lithotomy,pneumatic lithotripsy（PL）,Ho-YA Glithotripsy（HLL） and transurethral resection of the prostate（TURP） for benign prostatic hyperplasia patients with urinary bladder calculi.Methods 121 cases of benign prostatic hyperplasia patients with urinary bladder calculi from January 2010 to January 2015 were randomized into three groups：open surgery group（n =45）,PL group（n =39）and HLL group（n =37）.All patients were given tamsulosin 0.2 mg/d or finasteride 5 mg/d after operation.The intraoperative conditions,the postoperative index of the three groups were analyzed.Results Open surgery group had shorter stoneremoval time and operation time than those of the other two groups（P 〈 0.05）.The mean bleeding volume,peak flow rate of urine,length of stay,time of washing bladder and catheter retention time of PL group and HLL group were better than those of open surgery group（P 〈0.05）.There was significant difference in complication among the three groups（P 〉0.05）.Between PL group and HLL group only the difference of stone-removal time had significant difference（P 〈0.05）.Conclusion Compared with open operation,Pneumatic lithotripsy and Ho-YAG lithotripsy are more efficient and safe than suprapubic urinary bladder calculiotomy and has better clinical application value.
出处
《实用药物与临床》
CAS
2016年第2期204-207,共4页
Practical Pharmacy and Clinical Remedies
基金
国家自然科学基金(81572505)
关键词
良性前列腺增生
膀胱结石
气压弹道碎石术
钬激光碎石术
Benign prostatic hyperplasia
Urinary bladder calculi
Pneumatic lithotripsy
Ho-YAG lithotripsy
