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结节性胃炎与幽门螺杆菌的研究进展 被引量:4

Correlation of nodular gastritis with Helicobacter pylori infection
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摘要 结节性胃炎(nodular gastritis,NG)是幽门螺杆菌(Helicobacter pylori,H.pylori)主要作用于胃窦部的一种慢性胃炎的特殊形式,类似鸡皮疙瘩,淋巴滤泡增生是NG的组织学特征.目前全球H.pylori流行广泛,结节性胃炎是H.pylori感染的内镜下征象.行H.pylori根除治疗后NG患者临床表现、病理及内镜下表现均可显著改善,宜早作根除H.pylori工作.但目前关于NG的研究数据仍十分有限,其作为一个潜在的癌前病变以及胃十二指肠疾病的关系仍可疑,需要基于大量的随访研究.本文主要通过对NG与H.pylori相关性作一综述. Nodular gastritis(NG) is a form of chronic Helicobacter pylori(H.pylori) associated gastritis affecting the gastric antrum,which is characterized endoscopically by the presence of small nodular lesions resembling gooseflesh.It is generally accepted that NG is characterized histologically by hyperplasia of lymphoid follicles.At present,there is a wide range of H.pylori infections in the world,and NG is an endoscopic sign of H.pylori infection.After H.pylori eradication therapy,the clinical manifestations,pathology and endoscopic performance of NG patients can be improved significantly.Therefore,H.pylori eradication should be performed as early as possible in NG patients.The research data about NG is still very limited.The relationship between NG as potentially precancerous lesions and gastroduodenal diseases is still a debate and needs to be further explored.Here we review the research progress in understanding the correlation between NG and H.pylori.
出处 《世界华人消化杂志》 CAS 2015年第32期5177-5183,共7页 World Chinese Journal of Digestology
基金 国家科技惠民计划基金资助项目 No.2012GS620101 国家自然科学基金资助项目 Nos.81372145 81172366 甘肃省胃肠病重点实验室开放课题资助项目 No.gswcky-2013-003~~
关键词 结节性胃炎 幽门螺杆菌 淋巴滤泡性胃炎 根除治疗 Nodular gastritis Helicobacter pylori Follicular gastritis Eradication therapy
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