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血清SCC-Ag、VEGF联合检测在宫颈癌诊断中的意义 被引量:1

Value of joint detection of serum SCC-Ag and VEGF in the diagnosis of cervical cancer
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摘要 目的联合检测子宫颈癌患者血清中血清鳞状细胞癌抗原(SCC-Ag)和抗血管内皮生长因子(VEGF)水平,探讨其临床意义及两者的相关性。方法通过酶联免疫吸附试验法(ELISA)检测宫颈癌30例,宫颈上皮内瘤变(CIN)患者30例和正常人30名血清中SCC-Ag和VEGF的水平。结果宫颈癌组患者血清SCC-Ag和VEGF水平及阳性率均高于上皮内瘤变组及正常组,上皮内瘤变组高于正常组,差异有统计学意义(P<0.05)。结论联合检测宫颈癌患者血清中SCC-Ag和VEGF水平有助于判断患者的病情及预后,在临床上必将有着广阔的应用前景。 Objective To detect the levels of serum SCC-Ag and VEGF in cervical cancer and investigate their correlation and clinical application.Methods The levels of serum SCC-Ag and VEGF were measured by ELISA in 30 cases of healthy individuals,30 cases of cervical intraepithelial neoplasia and 30 cases of cervical cancer.Results The levels and positive rate of serum SCC-Ag and VEGF of group cervical cancer were signifi cantly higher than those of group cervical intraepithelial neoplasia and group healthy individuals,there were signifi cant differences between the three groups(P〈0.05).Conclusion The joint detection of serum SCC-Ag and VEGF has signifi cant diagnostic value for early stage cervical cancer.
作者 王卉
出处 《实用妇科内分泌电子杂志》 2015年第4期7-7,9,共2页 Electronic Journal of Practical Gynecological Endocrinology
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  • 1章杰捷,陈鲁,羊正炎.血清SCC-Ag对宫颈上皮内瘤变和早期宫颈癌的临床意义[J].肿瘤学杂志,2009,15(11):965-967. 被引量:4
  • 2程琪辉,孙淑华,孟祥兰.早期宫颈癌患者血清VEGF检测的临床意义[J].中国临床实用医学,2007,1(1). 被引量:3
  • 3张岚,张轶清.IGF-2、IGF-1R在早期宫颈癌中的表达及临床意义[J].安徽医学,2007,28(3):180-183. 被引量:3
  • 4曾瑄,王鹏,武莎斐,高洁,梁智勇,刘彤华.结直肠癌EGFR和HER2蛋白表达及其基因拷贝数分析[J].中华病理学杂志,2007,36(7):447-452. 被引量:8
  • 5Castle PE,Wheeler CM,Solomon D,et al.Interlaboratory reliability of hybrid capture 2.Am J Clin Pathol,2004,22:238-245.
  • 6Wang KL.Human papillomavirus and vaccination in cervical cancer.Taiwan J Obstet Gynecol,2007,46(4):352-362.
  • 7Plotti F, Nelaj E, Sansone M, et al. Sexual Function after ModifiedRadical Hysterectomy (Piver Ⅱ/Type B) vs. Classic Radical Hyster- ectomy (Piver Ⅲ/Type C2) for Early Stage Cervical Cancer.A Pro- spective Study [J]. J Sex Med, 2012, 9(3): 909-917.
  • 8葛鑫.鳞状上皮细胞癌抗原在子宫颈癌患者血清中的诊断价值[J].蚌埠瞑拳院学丰疆.2011.36(7):760-761.
  • 9Dehn D,Torkko KC, Shroyer KR Hrman Papilloma virus test- ing and moleculars of cervical dysplasia and carcinoma [J]. Cancer, 2007,111 ( 1 ) : 1-14.
  • 10Woodworth C D, Michael E,Marker D,et al. Inhibition ot the epidermal growth factor receptor increases expression of genes that stimulate inflammation,apoptosis,and cell attachment[J]. Mol Cancer Ther,2005,4(4) :650-658.

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