摘要
目的比较地佐辛与哌替啶在经皮肝穿刺胆道引流术(PTCD)中的镇痛效果。方法选择术前镇痛下实施PTCD治疗恶性梗阻性黄疸患者80例,随机分为试验组与对照组,每组各40例,试验组采用地佐辛术前镇痛,对照组采用哌替啶术前镇痛,使用疼痛数字评分(NRS)法评价术后疼痛程度,并对患者进行术前镇痛满意度测评,比较2组患者的镇痛效果。结果 2组均一次穿刺成功,引流操作顺利,术后黄疸均明显消退。术后试验组NRS为(2.34±0.75)分,满意度为88%,对照组的NRS为(4.03±0.89)分,满意度为68%,2组疼痛评分及满意度比较差异均有统计学意义(P均<0.05)。2组患者术中均未发生头晕、恶心、呕吐等不良反应。结论地佐辛与哌替啶用于PTCD术前镇痛均安全、有效。与哌替啶相比,地佐辛能更明显减轻患者术后疼痛,提升其满意度。
Obiective To compare the analgesic effect between dezocine and pethidine hydrochloride prior to the percutaneous transhepatic cholangial drainage （PTCD）.Methods Eighty patients diagnosed with malignant obstructive jaundice and treated with PTCD under preoperative analgesia were recruited and randomly divided into the experiemental （n =40）and control groups （n =40）.In the experimental group,patients were administered with dezocine for preoperative analgesia,and those in the control group were analgesized by pethi-dine hydrochloride.Numerical Rating Scale （NRS）was used to assess the severity of pain and satisfactory de-gree of preoperative analgesia.The analgesic effect was statistically compared between two groups.Results In both groups,PTCD was successfully performed by once puncture And the jaundice was significantly alleviated after PTCD.Postoperative NRS in the experimental group was （2.34 ±0.75）,significantly lower than （4.03 ±0.89）in the control group （P 〈0.05）.The satisfactory degree in the experimental group was 88%,signifi-cantly higher compared with 67.5% in the control group （P 〈0.05）.No signs of dizziness,nausea or vomi-ting were noted in both groups after PTCD.Conclusions Application of dezocine and pethidine hydrochloride are both safe and efficacious analgesia prior to PTCD.Compared with pethidine hydrochloride,use of dezocine could significantly alleviate postoperative pain and elevate patients＇degree of satisfaction.
出处
《新医学》
2015年第6期399-402,共4页
Journal of New Medicine
关键词
地佐辛
哌替啶
经皮肝穿胆管引流术
镇痛
Dezocine
Pethidine hydrochloride
Percutaneous transhepatic cholangial drainage
Analgesia
