摘要
目的探讨布地奈德雾化吸入治疗小儿急性喉炎的临床疗效。方法 54例患者随机分为治疗组和对照组各27例。均给予两组患者相同的综合性治疗和静脉给药地塞米松,治疗组同时加用布地奈德混悬液雾化吸入治疗。结果两组疗效比较,治疗组显效18例(66.7%)、有效9例(33.3%)、无效0例,总有效率100%;对照组显效12例(44.4%)、有效13例(48.1%)、无效2例(7.5%),总有效率92.5%,疗效差异有统计学意义(P<0.05)。治疗组平均嘶哑消失时间(1.1±0.9)d,平均犬吠样咳嗽消失时间(1.5±0.8)d,平均喉喘鸣消失时间(1.4±1.0)d,平均住院时间(7.0±2.5)d;对照组平均嘶哑消失时间(2.1±0.8)d,平均犬吠样咳嗽消失时间(2.7±1.1)d,平均喉喘鸣消失时间(2.4±0.7)d,平均住院时间(9.8±1.3)d。治疗组患儿症状消失时间和住院时间均少于对照组,差异有统计学意义(P<0.05)。结论布地奈德雾化吸入治疗小儿急性喉炎起效快、疗效显著、安全性高,值得临床推广使用。
Objective To study the curative effect of budesonide inhalation on acute laryngitis in chil-dren .Methods The patients were randomly divided into the observation group and the control group ,with 27 cases in each group .Both groups were given the same comprehensive treatment and dexamethasone , while the observation group was given budesonide inhalation in addition .Results In the observation group , 18 cases （66 .7% ） were cured ,9 cases （33 .3% ） got improved ,and the total effective rate was 100% .In the control group ,12 cases （44 .4% ） were cured ,13 cases （48 .1% ） got improved ,2 cases （7 .5% ） were ineffective ,and the total effective rate was 92 .5% .There existed significant difference in the effective rate between the two groups（ P〈0 .05） .The average time of hoarseness ,barking-like cough ,laryngeal stridor and the hospital stay was （1 .1 ± 0 .9）days ,（1 .5 ± 0 .8）days ,（1 .4 ± 1 .0）days and （7 .0 ± 2 .5）days in the observation group and （2 .1 ± 0 .8）days ,（2 .7 ± 1 .1）days ,（2 .4 ± 0 .7）days ,and（9 .8 ± 1 .3）days in the con-trol group respectively （ P〈0 .05） .Conclusion Atomizing inhalation of budesonide can produce good cura-tive effect on acute laryngitis in children .
出处
《山东医学高等专科学校学报》
2015年第2期93-94,共2页
Journal of Shandong Medical College
关键词
布地奈德
喉炎
雾化吸入
Budesonide
Laryngitis
Atomization inhalation
