摘要
目的对使用头孢菌素类药物联合其他药物进行治疗后出现不良反应的现象进行临床研究。方法 140例使用头孢菌素类药物联合其他药物进行治疗后出现不良反应的患者作为观察组,再选取未使用头孢菌素类药物联合其他药物进行治疗的60例患者作为对照组,比较分析出现不良反应的表现。结果观察组患者出现精神系统不良反应的比例为23.57%,出现再次被传染的比例为16.43%,出现消化系统不良反应的比例为19.29%,出现对肾功能的伤害的比例为13.57%,出现过敏现象的比例为15.00%,出现其他的不良反应情形的比例为12.14%,观察组患者的不良反应发生率高于对照组,组间治疗效果比较,差异具有统计学意义(P<0.05)。结论患者在进行药物使用时,必须做好防范工作,减少不良反应出现的情形,使药物的效果发挥的更彻底。
Objective To clinically research adverse reactions induced by cephalosporins drugs combined with other drugs. Methods There were 140 patients with adverse reactions induced by cephalosporins drugs combined with other drugs as observation group, and another 60 patients received no cephalosporins drugs combined with other drugs for treatment as control group. Manifestations of adverse reactions were comparatively analyzed. Results The observation group had proportion of adverse reactions in nervous system as 23.57%, proportion of reinfection as 16.43%, proportion of adverse reactions in digestive system as 19.29%, proportion of renal function damage as 13.57%, proportion of allergy as 15.00%, and proportion of other adverse reactions as 12.14%. The observation group had higher incidences of adverse reactions than the conlrol group, and the difference between the two groups had statistical significance （P〈0.05）. Conclusion It is necessary for good prevention work being applied in drug administration for patients, in order to reduce adverse reactions and to fully show drug effect.
出处
《中国现代药物应用》
2015年第13期44-45,共2页
Chinese Journal of Modern Drug Application
关键词
头孢菌素类
联合
其他药物
不良反应
Cephalosporins
Combination
Other drugs： Adverse reactions
