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精子形态与男性不育关系的研究 被引量:7

The relationship between sperm morphology and male infertility
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摘要 目的比较正常男性与不育症患者精液的检测指标,探讨男性不育与精子形态以及功能之间的关联性。方法收集215例男性不育患者的精液(实验组)和100例健康已生育男性的精液(健康对照组),分别检测2组精液的精子形态以及精子功能。检测项目包括精液的颜色、精液量、酸碱度、液化时间、精子数量、显微镜观察精子形态以及精子的活动度。结果实验组和健康对照组比较,精液颜色、精液量、液化时间以及酸碱度差异无统计学意义(P>0.05)。但在精子活力方面,实验组精子头部、体部以及尾部畸形的比例均显著高于健康对照组(20.8%和9.5%;15.7%和7.4%;27.3%和11.6%),差异有统计学意义(P<0.05)。实验组A级和A+B级精子活力(13.1±5.21)%,(27.5±4.86)%,明显低于健康对照组(33.5±5.34)%,(62.4±4.57)%,差异有统计学意义(P<0.05)。结论精子的形态和活力是影响男性不育的重要原因。 Objective To explore the relationship between the semen of male infertility and healthy male, and to clarify the relationship between male infertility and sperm morphology and function. Methods 215 cases of male infertility patients' semen (experimental group) and 100 cases of normal male semen (control group) were collected, and then the sperm morphology and function of these two groups were detected. The test items included the sperm color,quantity,pH,liquefaction time, sperm morphology and vitality. Results There was no significant difference on sperm color, sperm quantity, liquefaction time and sperm pH between experimental and control group (P〉0.05), but there was a significant difference in head, body and tail abnormalities between this two groups (20.8% and 9.5%; 15.7% and 7.4% ;27.3% and 11.6% ;P〈0.05). Besides,sperm vitality of A and A+B in infertile group is much lower than control group[(13.1±5. 21) %,(27.5±4.86) % ;(33.5±5.34) %,(62.4±4.57) %;P〈0. 05]. Conclusion Sperm morphology and vitality are very important impact factors for male infertility.
作者 曹珂 刘会彩
出处 《检验医学与临床》 CAS 2015年第11期1570-1571,1574,共3页 Laboratory Medicine and Clinic
关键词 精子形态 精子功能 男性不育 sperm morphology sperm activity male infertility
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