摘要
目的:分析轮状病毒感染对婴幼儿心肌的损伤及相关影响。方法:选择我院收治的轮状病毒感染患儿164例,根据是否发生心肌损伤分为观察组60例与对照组104例。对两组患儿的心电图、心肌酶谱和心肌肌钙蛋白I(c Tn-I)进行检测对比。分析年龄、机体代谢紊乱等因素对轮状病毒感染患儿心肌功能的影响,并比较观察组患儿治疗前后心肌酶谱指标的变化。结果:观察组心肌酶谱CK、CK-MB、AST、LDH、LDH1、CTn-I、LDH1/LDH2测定值均显著高于对照组(P<0.05);年龄<1岁、中重度脱水、腹泻、低钾血症以及酸中毒为发生心肌损伤的高危因素;经治疗后心肌损伤的患儿心肌酶谱指标比治疗前均显著降低(P<0.05)。结论:年龄<1岁、脱水、腹泻、低钾血症以及酸中毒严重的轮状病毒感染患儿容易发生心肌损伤,临床上应加强对其心肌酶谱的检测,在治疗腹泻基础上注意对心肌功能的保护,做到早诊早治,以避免患儿心肌功能的进一步损伤。
Objective： To analyze rotavirus infection injury and related effects on infant myocardium. Methods：Among 164 cases of rotavirus infection infants in our hospital,60 cases were allocated into observation group and104 cases of control group according to the occurrence of myocardial injury. ECG,myocardial enzyme spectrum and c Tn-I of the two groups were detected and compared. Age,metabolic disorders and other factors on myocardial function of children with rotavirus infection were analyzed and the changes of myocardial enzyme indexes were compared before and after the treatment. Results： The detected value of CK,CK-MB,AST,LDH,LDH1,CTn-I,LDH1 / LDH2 of the observation group were significantly higher than those of control group（ P 0. 05）.Conclusion： Ages one year old,severe dehydration,diarrhea,hypokalemia and acidosis were risk factors of myocardial injury. The observation of myocardial enzymes should be a primary concern,also myocardial function should be protected on the basis of treating diarrhea. Early detection and early treatment can avoid further injury of myocardial function in patients.
出处
《现代医学》
2015年第3期343-346,共4页
Modern Medical Journal
关键词
轮状病毒
婴幼儿
心肌损伤
心肌酶谱
rotavirus
infant
myocardium injury
myocardial enzyme spectrum
