摘要
目的 对比口服阿奇霉素与静滴红霉素治疗小儿文原体肺炎的疗效及不良反应。方法将105例病人随机分为A组54例和B组51例。A、B两组分别口服阿奇霉素片5～1mg/（kg·d）和静滴红霉素注射剂20～40mg/（kg·d）。观察临床痊愈率、有效率、病原体清除率及不良反应发生率，并对结果进行统计学分析。结果 临床痊愈率、有效率、病原体清除率A组分别为59．25％、94．44%和75．9%，B组分别为37．25％、74．51％和54．90％。A组优于B组，并有显著性差异，不良反应发生率A组7．41％，B组37．25％，A组低于B组。结论 口服阿奇霉素和静滴红霉素治疗小儿支原体肺炎均有较好疗效，但前者疗效更优，清除肺炎支原体的功能更强，而且不良反应发生率较低。
ABSTRACT: To compare the efficacy and adverse reaction of azithromycin (AT) by oral and erythromycin (EM) by intravenousdrip in treating podiatric mycoplasmal pneumonia. 105 patients were randomly divided into group A (AT group, n = 54) and group B (EMgroup, n = 51 ), AT in oral dosage of 10mg/(kg. d) and ET in intravenous dosage of 20～40mad(kg. d) were given respectively. Resultsshowed that the curative rate, effective rate and clearance rate of mycoplasma in AT group were higher than those in EM group with significantdifferences. The adverse reactions induced by oral AT were less than those by infused EM. Both oral AT and infused EM displayedsatisfactory therapeutic effect, but oral AT shows higher curative rate and myycoplasmal clearance rate, and less adverse reactions.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2002年第4期240-242,共3页
Chinese Journal of Antibiotics
关键词
阿奇霉素
红霉素
肺炎
支原体感染
治疗
小儿
KEYWORDS: Azithromycin
Erythromycin
Pneumonia
Mycoplasmal infection
