摘要
目的:观察长蛇灸对阳虚体质者血清促肾上腺皮质激素(ACTH)及皮质醇(CORT)的影响,探讨长蛇灸改善阳虚体质作用机制。方法:将90例阳虚体质者随机分为长蛇灸组和阳虚对照组,每组45例;45例平和体质者作为平和对照组。长蛇灸组每周施行长蛇灸1次,4次为1个疗程,共3个疗程。在治疗前、治疗结束时及治疗结束6个月,分别记录阳虚质量表评分,放射免疫法检测血清ACTH、CORT含量。结果:与治疗前比较,长蛇灸组治疗结束时阳虚质量表评分明显降低(P<0.01);治疗前,与平和对照组比较,长蛇灸组及阳虚对照组阳虚质量表评分明显升高(P<0.01);治疗结束时,与平和对照组比较,阳虚对照组阳虚质量表评分明显升高(P<0.01)。与本组治疗前比较,长蛇灸组在治疗结束时血清ACTH及CORT含量明显升高(P<0.01);治疗前,与平和对照组比较,长蛇灸组及阳虚对照组血清ACTH及CORT含量明显降低(P<0.01);治疗结束时,与平和对照组比较,阳虚对照组血清ACTH及CORT含量明显降低(P<0.01);治疗结束6个月时,与平和对照组比较,阳虚对照组血清CORT含量明显降低(P<0.01);长蛇灸组、阳虚对照组及平和对照组在治疗结束6个月的阳虚质量表评分分数、血清ACTH含量及血清CORT含量与本组治疗结束时相差不大(P>0.05)。结论:长蛇灸疗法有可能是通过提高血清ACTH及CORT含量从而达到改善阳虚体质的作用。
Objective Yang deficiency constitution may bring with different types of illnesses in many people.The present study was designed to observe the effect of ginger-separated snake moxibustion on yang deficiency symptom,and serum adrenocorticotropic hormone (ACTH)and cortisol (CORT)contents in yang deficiency constitution subjects,so as to explore its mechanism underlying improvement of yang deficiency constitution.Methods Ninety subjects with yang deficiency type consti- tution were equally and randomly assigned to control A group (19men and 26women,18--60years in age)and moxibustion group (16men and 29women,18-60years in age)and 45normal subjects with mild constitution (18men and 27women,18-60 years in age)were assigned to control B group.An snake-like moxa-cone was placed at a moxa-holder covering the middle back of human body from Dazhui (GV 14)to Yaoshu (GV 2)after paving a layer (about 1 cm thick)of fresh ginger in the holder,and then ignited,followed by the next moxa-cone,3cones altogether every time for each participant.The treatment was conducted once a week,12 times in total.The subjects'constitution was scored according to the "Classification and Evaluation of Constitution of Traditional Chinese Medicine"formulated by China Association of Chinese Medicine.The serum ACTH and CORT contents were measured by radioimmunoassay before and at the end of the treatment and 6months after the treatment.Results The constitation scores of the moxibustion group and control A group were significantly higher than that of the control B group before treatment (P<0.01).At the end of the treatment,the constitution score was significantly decreased in the moxibustion group (P<0.01)rather than in the control A group relevant to its own pre-treatment (P>0.05).The serum CORT and ACTH contents were significantly decreased in both the moxibustion and control A groups in comparison to the control B group before treatment (P<0.01),and obviously increased at the end of treatment in the moxibustion group compared with its own pre-treatment (P<0.01).No significant differences were found among the three groups in the constitution score,and serum CORT and ACTH levels at the 6th month after the treatment compared with their own post-treatment (P>0.05)Conclusion The ginger-separated snake moxibustion treatment may improve the constitution of yang deficiency participants by increasing the levels of serum ACTH and OORT,which may be helpful in resisting diseases.
作者
胡秀武
邓陈英
唐丽梅
邱芬芬
黄平
耿乐乐
刘建武
王富春
王之虹
HU Xiu-wu;DENG Chen-ying;TANG LI-mei;QIU Fen-fen;HUANG Ping;GENG Le-le;LIU Jian-wu;WANG Fu-chun;WANG Zhi-hong(Department of Acupuncture and Moxibustion,Nanchang Hongdu Hospital of Traditional Chinese Medicine,Nanchang 330006,China;Department of Rehabilitation,Nanchang Hospital of Integrated Traditional Chinese and Western Medicine,Nanchang 330006;Department of Acupuncture and Moxibustion,the Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanehang 330006;Institute of Acupuncture and Moxibustion,Changchun University of Traditional Chinese Medicine,Changchun 130000)
出处
《针刺研究》
CAS
CSCD
北大核心
2018年第12期773-776,共4页
Acupuncture Research
关键词
长蛇灸
阳虚质
促肾上腺皮质激素
皮质醇
Ginger-separated snake moxibustion
Yang deficiency constitution
Adrenocorticotropic hormone
Cortisol