摘要
目的探讨昆明地区有消化道症状儿童幽门螺杆菌(HP)感染的流行情况及流行趋势,为做好防治工作提供依据。方法采用回顾性分析对2013年1月至2016年12月有消化道症状3~18岁12932例儿童进行13C尿素呼气试验检查,并对儿童HP流行趋势、年龄和性别HP流行特征进行统计学分析。结果昆明地区2013年至2016年有消化道症状的儿童HP感染率分别为17.85%、18.26%、20.41%、32.93%,儿童HP总感染率24.08%(3114/12932),其中男孩感染率为24.82%(1706/6874),女孩感染率为23.24%(1408/6058),男孩HP感染率高于女孩,男女孩HP感染阳性率比较差异有统计学意义(P<0.05),随年龄的增长,HP感染率逐渐增高;11~14岁年龄段男孩、女孩HP感染[29.03%(349/1202)比22.62%(190/840)]比较差异有统计学意义(P<0.05)。结论昆明地区消化道症状儿童HP感染率有逐年上升的趋势,HP感染率与性别、年龄有关,男孩感染率高于女孩,且阳性率与年龄因素呈正比。
Objective To investigate the prevalence and trend of Helicobacter pylori(HP)infection in children with gastrointestinal symptoms in Kunming area,and to provide basis for prevention and cure.Methods All of 12 932 cases with gastrointestinal symptoms were adopted by retrospective analysis method from January 2013 to December 2016,and HP infection was detected by 13C-urea breath test(13C-UBT).The epidemioloqical characteristics of children with HP infection in including prevalence trend and gender and age HP were statistically analyzed.Results The rates of HP from January 2013 to December 2016 were respectively 17.85%,18.26%,20.41% and 32.93%.The rate of HP positive was 24.08%(3 114/12 932),which was 24.82%(1 706/6 874)in boys and 23.24%(1 408/6 058)in girls.The rate of HP infection was significantly higher in boys than that in girls,and there was statistical differences(P<0.05).The rate of HP infection showed a gradual upward trend with age.There was statistical differences in gender between age 11 and 14[(29.03%(349/1 202)vs.22.62%(190/840)](P<0.05).Conclusions HP infection rate is high in the children with gastrointestinal symptoms in Kunming,and the rate of HP infection in children is related with gender.The rate of HP infection is significantly higher in boys than that in girls,and the positive rate is directly proportional.
作者
符甜甜
王美芬
陈韬
王明英
段金涛
方佳慧
Fu Tiantian;Wang Meifen;Chen Tao;Wang Mingying;Duan Jintao;Fang Jiahui(Department of Gastroenterology,the Children's Hospital Affiliated of Kunming Medical University,Kunming City Children's Hospital,Kunming 650228,China)
出处
《中国医师进修杂志》
2018年第12期1070-1073,共4页
Chinese Journal of Postgraduates of Medicine
基金
云南省昆明市卫生人才培养及十百千工程项目(2016-sw省-53).
关键词
螺杆菌
幽门
儿童
感染率
Helicobacter pylori
Children
Infection rate
