摘要
用透射电镜及能谱仪对10例间皮瘤患者肺组织样品进行配对研究,结果表明,闪石类石棉纤维中青石棉和铁石棉纤维的含量病例组与对照组比较有非常显著性差异(P<0.001)。温石棉及其他纤维分布极为相近,两组间无显著性差异(P>0.05)。相对危险度与闪石类≥5μm的长纤维、直径<0.3μm的细纤维含量有关;与闪石类<5μm的短纤维、直径≥0.3μm的粗纤维、温石棉长短纤维及其他各类纤维无关。此结果为间皮瘤的病因学提供了依据。
Matching study of the lung tissue samples from the autopsy of 10 mesothelioma patients was donewith the transmission electron microscope and the energy dispersive spectroscope. The results showedthat the concentration of amphibole fibers of the case group was significantly higher than that of thecontrol (P<0. 001). The distributions of chrysotile and all other fibers in the two series were similarand not significantly different (P>0. 05). Relative risk was related to the contents of amphibolefibers with length≥5μm--long fibers or with diameter<0. 3μm～thin fibers, and was not related tothose length<5μm--short fibers or diamater>0. 3μm thick fibers. Nor was it related to chrysotile andall other fibers. The basic mesothelioma pathogeny was provided by the research described in this pa-per.
出处
《河南医科大学学报》
1991年第4期317-321,共5页
Journal of Henan Medical University
关键词
石绵纤维
间皮肿瘤
肺组织
asbestos fiber
mesothelioma
lung
electron microscope
