摘要
目的探讨副肿瘤性天疱疮原发肿瘤的临床病理及超声表现,以提高对本病超声图像特征的认识及早期诊断率。资料与方法回顾性分析经免疫学检查及病理确诊的11例副肿瘤性天疱疮患者,分析其临床病理及超声图像特征。结果 11例患者中,5例Castleman病,3例滤泡树突状细胞肉瘤,2例B细胞性非霍奇金淋巴瘤,1例炎性肌纤维母细胞瘤。超声显示Castleman病、滤泡树突状细胞肉瘤及炎性肌纤维母细胞瘤均呈形态规则或分叶状低回声肿块,9例中7例病灶表现为回声不均匀;B细胞性非霍奇金淋巴瘤显示为特异性,形态规则、回声极低较均匀。5例Castleman病中4例边界清晰,3例内部回声不均匀,散在细条状高回声,1例伴有病灶内部钙化灶;3例滤泡树突状细胞肉瘤均表现为回声不均匀,散在粗细不等的条状高回声,2例边界不清,2例伴钙化灶;1例炎性肌纤维母细胞瘤表现为低回声背景上的散在细条状高回声。彩色多普勒血流显像示10例病灶血流丰富,呈周边粗大环绕血流伴内部穿支血流的模式。结论由于副肿瘤性天疱疮不同类型原发肿瘤的超声图像具有共同特点,超声检查对病灶的早期发现可以为临床诊断提供重要依据。
Purpose To investigate the clinical pathology and ultrasound characteristics of underlying diseases of paraneoplastic pemphigus（PNP）.Materials and Methods The clinical data,pathological information and ultrasound images of 11 cases of immunologically and pathologically diagnosed PNP were retrospectively reviewed.Results There were 5 cases of Castleman’s disease（CD）,3 cases of follicular dendritic cell sarcoma（FDCS）,2 cases of B-cell non-Hodgkin’s lymphoma（NHL） and 1 case of inflammatory myofibroblastic tumor（IMT）.NHL manifested as specific regular and homogeneous masses extremely hypoechoic,the other 9 cases of CD,FDCS and IMT were regular or lobulated hypoechoic masses and 7 of them were heterogeneous.Of 5 CDs,4 had clear margins,3 were heterogeneously hypoechoic with scattered hyper-echoic thin strips,and 1 had internal calcification.Three cases of FDCS showed heterogeneous hypoechoic mass with scattered,various thickness hyper-echoic strips,and 2 were illdefined and 2 had calcifications.The 1 case of IMT demonstrated as scattered hyper-echoic thin strips on the background of heterogeneous low echo.On color Doppler imaging,10 of 11 lesions showed abundant peripheral and internal penetrating blood flows.Conclusion Ultrasound screening can be a useful tool for early detecting the underlying tumors of PNP since they characteristics in common.
出处
《中国医学影像学杂志》
CSCD
北大核心
2014年第6期437-440,共4页
Chinese Journal of Medical Imaging
