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氯胺酮治疗难治性抑郁症的进展与机制 被引量：9

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摘要 抑郁症是一种常见的精神障碍，我国抑郁症的患病率虽然较西方国家略低，但终生患病率仍然高达5．3％。现有的抑郁症治疗药物大多作用于单胺递质系统，但起效往往较慢，且疗效不尽如人意，尤其对于伴有自杀倾向的患者这一问题更显突出。因此研究者不断对作用其他递质系统的抗抑郁药进行探索，其中作用于谷胺酸系统的氯胺酮近年来受到重视。我们对氯胺酮在难治性抑郁症方面的研究进展进行了综述。
作者 马云 毛佩贤 任艳萍 汤宜朗 马辛
机构地区 首都医科大学附属北京安定医院老年科 首都医科大学附属北京安定医院科教科
出处 《中华精神科杂志》 CAS CSCD 北大核心 2014年第3期183-185,共3页 Chinese Journal of Psychiatry
关键词 难治性抑郁症 治疗药物 氯胺酮 单胺递质系统 终生患病率 精神障碍 西方国家 自杀倾向
分类号 R749.4 [医药卫生—神经病学与精神病学]
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参考文献32

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二级参考文献10

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共引文献36

同被引文献91

引证文献9

二级引证文献108

中华精神科杂志
2014年 第3期

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