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我国14岁以上人群支气管哮喘患病危险因素的调查分析 被引量:49

Risk factors of bronchial asthma among people aged over 14 years in China
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摘要 目的 调查分析我国14岁以上人群支气管哮喘(简称哮喘)患病的危险因素.方法 2010年2月至2011年8月采用多级随机整群抽样方法,以全国8个省(市)年龄>14岁的常住居民作为研究对象进行入户问卷调查,了解全国哮喘患病情况及相关危险因素,根据病史、体征和肺功能检查确诊哮喘患者,采用SPSS 12.0软件进行统计学分析,探讨我国哮喘患病危险因素的流行病学分布特点.结果 共入户调查180 099人,回收有效调查问卷164 215份.入组的164 215人中男79 692人、女84 523人;诊断哮喘患者2 034人,哮喘总体患病率为1.2%(2 034/164215).相关因素分析显示,吸烟(OR=1.697,95%CI:1.547 ~1.861)、母乳喂养(OR=0.801,95% CI:0.670~0.959)、遗传因素[OR值及相应95% CI亦均大于l,以哮喘最为显著(OR=10.440,95%CI:8.991 ~12.112)]、各种合并症(OR值及相应95% CI亦均大于1)、体质指数(与正常体重比较,超重的OR=1.360,95%CI:1.212~1.531;肥胖的OR=10.631,95%CI:9.570 ~ 11.801)、各种宠物饲养(OR值及相应95% CI均大于1)是哮喘的危险因素.结论 我国14岁以上人群哮喘患病危险因素众多,既包括宿主因素如遗传因素、肥胖,也包括吸烟、母乳喂养、合并症、宠物饲养等环境因素,应予以高度重视. Objective To survey the risk factors of asthma among the people aged over 14 years in China.Methods Home visits for completing epidemiological questionnaires in accordance with stratified cluster random sampling survey were conducted in 8 provinces (cities) of China residents aged over 14 years from February 2010 to August 2011.Asthma was diagnosed based upon case history,clinical signs and lung function test.The SPSS 12.0 software was used for statistic analyses for the epidemiological status of asthma.Results Sampling population was composed of 180 099 subjects.Among 164 215 valid questionnaires,there were 79 692 males and 84 523 females,2 034 had asthma.The overall prevalence rate was 1.2% (2 034/164 215).Correlation analyses showed that the risk factors were smoking (OR =1.697,95% CI:1.547-1.861),breast feeding (OR =0.801,95% CI:0.670-0.959),genetics (OR & 95% CI > 1,asthma (OR =10.440,95% CI:8.991-12.112)),complications (OR & 95% CI > 1),body mass index (compared with normal weight,overweight (OR =1.360,95% CI:1.212-1.531),obesity (OR =10.631,95%CI:9.570-11.801)) and petting (OR & 95%CI > 1).Conclusion Among Chinese asthmatics aged over 14,their risk factors include host (genetics & obesity) and environmental (smoking,breastfeeding,complications & pets) factors.
出处 《中华医学杂志》 CAS CSCD 北大核心 2014年第16期1209-1214,共6页 National Medical Journal of China
基金 中华医学会临床医学科研专项资金(07010400048) 首都医学发展科研基金(2007-1011)
关键词 哮喘 患病率 危险因素 流行病学 Asthma Prevalence Risk factors Epidemiology
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