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三唑类化合物的合成及抑菌活性 被引量:3

Synthesis of triazole compounds and evaluation of their antimicrobial activities
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摘要 为了获得高活性的木材防腐剂,以1,3-二氯苯为原料,依次经过傅克酰基化、烷基化、环氧化及开环反应得到6种三唑类化合物Y-4(a-f),且所有化合物的结构经过MS和1H-NMR确定;采用滤纸片法对常见的两种霉菌和两种木腐菌进行活性抑菌实验。结果表明:6种化合物中,Y-4d表现出的抗菌谱较广,对木材霉菌和腐朽菌都有抑制作用,但对腐朽菌的抑制效果不如Y-4c和Y-4f,Y-4c和Y-4f对木材腐朽菌表现出较强的抑制能力。 In order to get a wood preservative with higher efficiency, six compounds Y-4( a-f) were synthesized using 1, 3-dichlorobenzene as the starting material by Friedel-crafts acetylation, alkylation, epoxidation, and ring-opening re-action. The structures of these compounds were determined by MS and 1 H-NMR. Antifungal activities of these compounds were evaluated by two moulds and two decay fungi with Filter paper diffusion. The results indicated that Y-4d had a broad spectrum of antibacteria on moulds and decay fungi, but Y-4c and Y-4f had better antibacterial effect on decay fungi.
出处 《南京林业大学学报(自然科学版)》 CAS CSCD 北大核心 2014年第2期161-164,共4页 Journal of Nanjing Forestry University:Natural Sciences Edition
基金 国家林业公益性行业科研专项项目(201104032)
关键词 三唑类化合物 抑菌效果 木材防腐剂 triazole antibacterial effect wood preservatives
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