摘要
目的 比较保乳手术与改良根治术治疗早期乳腺癌的临床疗效及对患者生活质量的影响.方法 将78例早期乳腺癌患者按照随机数字表法分为两组,每组各39例,其中对照组采取改良根治术,观察组实施保乳手术,比较两组临床疗效、手术情况及生活质量评分.结果 观察组手术时间、术中出血量、切口长度及平均住院时间分别为（60.23±5.21） min、（44.73±4.22） mL、（4.72±1.02）cm和（9.52±0.86）d,均显著少于对照组（t=7.88、8.32、8.89、6.42,均P＜0.05）;观察组术后躯体因子、精神因子、心理因子及社会因子等方面评分分别为（67.44±3.87）分、（48.64±3.73）分、（117.34±8.33）分和（61.56±5.32）分,均显著高于对照组（=5.43、5.87、6.29、7.11,均P＜0.05）;两组术后3年局部复发、远处转移及生存率比较差异均无统计学意义（x2=1.22、1.09、1.29,均P＞0.05）.结论 保乳手术治疗早期乳腺癌效果显著,具有创伤小、出血少和美容效果好的优势,可作为早期乳腺癌治疗的首选方法,值得临床进一步推广和应用.
Objective To compare the clinical efficacy of breast-conserving surgery and modified radical mastectomy for early breast cancer and their influence on quality of life. Methods 78 patients with early stage breast cancer were divided into two groups by random number table, and 39 cases in each group. The control group was given modified radical mastectomy, while the observation group was given breast-conserving surgery. The clinical effi- cacy, surgical conditions and quality of life scores were compared between the two groups. Results The operative time,blood loss, incision length and the average hospital stay of the observation group were （60.23 ± 5.21 ）rain, （44. 73 ±4.22） mL, （4.72 ± 1.02） em and （9.52±0.86） d, which were significantly lower than those of the control group（ t = 7.88,8.32,8.89,6.42, all P 〈 0.05 ）. The postoperative physical factors, mental factors, psychological factors and social factors scores of the observation group were （ 67.44 ± 3.87 ）, （ 48.64 ~ 3.73 ）, （ 117.34 ~ 8.33 ） and （61.56 ~ 5.32）, which were significantly higher than those of the control group （ t = 5.43,5.87,6.29,7.11, all P 〈 0.05 ）. The postoperative 3-year local recurrence, distant metastasis and survival rate showed no significant differ- ences between the two groups（ X2 = 1.22,1.09,1.29, all P 〉 0.05 ）. Conclusion Breast-conserving surgery in the treatment of early breast cancer has significant effect, and it has less trauma, less bleeding and cosmetic results, and it can be used as the preferred method for the treatment of early breast cancer, which is worth to be further applied in clinical.
出处
《中国基层医药》
CAS
2014年第6期870-871,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
乳腺肿瘤
保乳手术
改良根治术
生活质量
Breast neoplasms
Breast-conserving surgery
Modified radical mastectomy
Quality of life
