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抗生素骨水泥链珠在创伤性骨髓炎治疗中的应用 被引量:11

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摘要 目的探讨抗生素骨水泥链珠(以下简称抗生素链珠)对创伤性骨髓炎的治疗效果。方法 42例创伤性骨髓炎患者,其中胫骨、肱骨中段骨干感染24例,胫骨干骺端骨感染18例。骨缺损3 cm×4 cm^8 cm×5 cm,软组织缺损6 cm×4 cm^10 cm×4 cm。42例患者均行创面彻底清创,去除坏死及感染的骨组织及软组织,截除骨折端坏死骨质,反复冲洗创面后予抗生素链珠充填,创面行负压封闭引流(VSD)。24例骨干感染者待创面炎症反应消除后取出抗生素链珠,行植骨术;18例干骺端感染者待创面脓性分泌物较少后再次清创(取出临时抗生素链珠),永久植入抗生素链珠。术后随访6~36个月,观察创面愈合时间、X线表现、感染复发情况等。结果本组病例创面愈合时间21~39 d、平均29 d。随访6~36个月,X线片示所有骨痂生长良好,植骨部分已融合,未再发现死骨及空洞。结论抗生素链珠充填联合VSD是治疗创伤性骨髓炎的较好方法。
出处 《山东医药》 CAS 2014年第6期59-61,共3页 Shandong Medical Journal
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同被引文献97

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