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血浆或效应室靶浓度靶控输注丙泊酚诱导对中青年患者血流动力学的影响 被引量：7

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摘要 目的以血浆靶浓度或效应室靶浓度为目标靶控输注丙泊酚全麻诱导,探讨其对中青年患者血流动力学的影响.方法选年龄31～50岁行择期手术的中青年患者40例,随机分为血浆靶浓度组（A组）和效应室靶浓度组（B组）,各20例.A组设定血浆靶浓度为4μg/mL,B组设定效应室靶浓度为4μg/mL.记录两组效应室浓度达到4μg/mL的时间及用药剂量;记录两组效应室浓度达到4μg/mL时血流动力学的监测值和脑电双频指数（BIS）测定值.结果两组患者在全麻诱导过程中BIS、HR、MAP、CI、SI、SVR、ACI、LCWI差异无统计学意义（P〉0.05）;B组效应室浓度达到4μg/mL的时间明显短于A组（P〈0.01）,B组诱导丙泊酚用量少于A组（P〈0.01）,而且不良心血管事件无明显增加.结论中青年患者全麻诱导中,丙泊酚以效应室靶浓度为目标的靶控输注能明显缩短麻醉诱导时间,且过程平稳,用药量更少.
作者 黄肇敏 欧阳葆怡 黄焕森
机构地区 广州医科大学附属第一医院麻醉科 广州医科大学附属第二医院麻醉科
出处 《广东医学》 CAS CSCD 北大核心 2014年第1期91-93,共3页 Guangdong Medical Journal
关键词 丙泊酚 靶控输注 诱导 血流动力学
分类号 R614.24 [医药卫生—麻醉学]
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参考文献7

二级参考文献20

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共引文献48

同被引文献64

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引证文献7

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广东医学
2014年 第1期

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