摘要
目的调查社区人群高血压患者中焦虑障碍及抑郁障碍的患病情况，分析高血压共病焦虑及抑郁障碍的危险因素。方法2011年4—12月在北京城市和农村社区中共调查807例高血压患者，应用复合性国际诊断交谈表3．0计算机版（CIDI-3．0）作为焦虑障碍和抑郁障碍的诊断工具进行测评，评定高血压患者中焦虑障碍和抑郁障碍的患病率，并分析相关的危险因素。结果社区人群高血压患者中焦虑障碍的患病率为23．3％，抑郁障碍的患病率为5．7％。多因素Logistic回归分析得出，高血压患者共病焦虑障碍危险因素为：未规律治疗（OR=4．500；95％CI：2．431—8．331），吸烟（OR=1．805；95％CI：1．036—3．145），体力劳动者（OR=1．933；95％CI：1．223～3．053），高血压分级2级及以上（OR=1．525；95％CI：1．041～2．234）。高血压共病抑郁障碍的危险因素为：未规律治疗（OR=5．333；95％CI：1．554—18．304），服用利血平或含有利血平成分的降压药（OR=6．667；95％CI：1．981～22．435），独身（OR=5．000；95％cI：1．096～22．820）。结论社区人群高血压患者中焦虑障碍的患病率高于抑郁障碍。未规律治疗是高血压人群共病焦虑障碍和抑郁障碍共同的危险因素。此外，吸烟、体力劳动者、高血压分级2级及以上的高血压患者容易共病焦虑障碍，独身、服用利血平或含利血平成分降压药的高血压患者容易共病抑郁障碍。
Objective To explore the prevalence of hypertensive patients with co-morbid anxiety and/or depression and determine the risk factors of eomorbidity in community. Methods A cross-section study was performed among 807 hypertensive patients in urban and rural community settings of Beijing in 2011. The Composite International Diagnostic Interview, computer assisted personal interview （CIDI-3.0- CAPI） was administrated by face-to-face interview. And the diagnosis of anxiety and depression was made according to the definitions and criteria of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition （DMS-IV）. The prevalence and related risk factors of hypertensive patients with comorbid anxiety and/or depression were reported. Results It was found that 23.3% of patients were accompanied with anxiety and 5. 7% with depression in hypertensive patients in community. The risk factors of anxiety included irregular treatment （ odds ratio 4. 500; 95% confidence interval, 2. 431 to 8. 331 ） , smoking （ 1. 805 ; 1. 036 to 3. 145）, manual labor （ 1. 933 ; 1. 223 to 3. 053） and two or above stage of hypertension （ 1. 525 ; 1. 041 to 2. 234）. And the risk factors of depression included irregular treatment （5. 333 ; 1. 554 to 18. 304）, taking reserpine or ingredients containing reserpine （6. 667 ; 1. 981 to 22. 435 ） and singlehood （5. 000; 1. 096 to 22. 820 ）. Conclusion The prevalence of anxiety is higher than depression in hypertensive patients in community. Irregular treatment is the common risk factor of anxiety and depression. Patients with smoking, manual labor and two or above stage of hypertension are more likely to have a coexistence of anxiety while those unmarried, taking reserpine or ingredients containing reserpine are more likely to suffer from depression.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2014年第1期62-66,共5页
National Medical Journal of China
基金
国家科技支撑计划项目（2009BA177806）
关键词
高血压
焦虑
抑郁
现况调查
Hypertension
Anxiety
Depression
Cross-sectional studies
